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Peptide record

TPDB12137

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12137
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFTKFAGKGIKDLIFKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC
Physicochemical Analysis
C221H371N59O56S3
NQPSWY
G
4846.92
10.11
10
4
20
+5
8.63
0.467
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.58
3
Residue Composition
number
2
A
1
R
0
N
3
D
2
C
1
E
0
Q
9
G
1
H
6
I
2
L
8
K
1
M
3
F
0
P
0
S
1
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 3 C: 2 E: 1 Q: 0 G: 9 H: 1 I: 6 L: 2 K: 8 M: 1 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 6
Chemical Descriptors
46
C221H371N59O56S3
4846.92
10.11
+5
8.63
0.467
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
2.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
5.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
5.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
2.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
5.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
2.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
5.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
5.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
2.8 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 5.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
5.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 2.8 ug/ml), Gram+ bacteria S. aureus (MIC 2.8 ug/ml), and yeast C. albicans (MIC 5.6 ug/ml). Updated 7/2021