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Peptide record

TPDB12135

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12135
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRVGIDVAGCKIKGVC
Physicochemical Analysis
C220H370N60O55S3
QPTWY
G
4831.91
10.32
10
3
20
+6
7.81
0.465
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.59
4
Residue Composition
number
2
A
1
R
1
N
2
D
2
C
1
E
0
Q
9
G
1
H
6
I
2
L
8
K
1
M
3
F
0
P
1
S
0
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 2 C: 2 E: 1 Q: 0 G: 9 H: 1 I: 6 L: 2 K: 8 M: 1 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 6
Chemical Descriptors
46
C220H370N60O55S3
4831.91
10.32
+6
7.81
0.465
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
1.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
1.7 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
3.4 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
1.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
1.7 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
3.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
1.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
1.7 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
3.4 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
1.7 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 3.4 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
1.7 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 3.4 ug/ml), Gram+ bacteria S. aureus (MIC 1.7 ug/ml), and yeast C. albicans (MIC 1.7 ug/ml). Updated 7/2021