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Peptide record

TPDB12133

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12133
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFSKISGKAIKNLFIKGAKNVGKEVGIDVVRTGMDVVGCKIKGEC
Physicochemical Analysis
C213H365N59O60S3
QHPWY
GK
4808.78
10.11
9
4
18
+5
11.24
0.215
101.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.60
7
Residue Composition
number
2
A
1
R
2
N
2
D
2
C
2
E
0
Q
8
G
0
H
6
I
1
L
8
K
1
M
2
F
0
P
2
S
1
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 2 C: 2 E: 2 Q: 0 G: 8 H: 0 I: 6 L: 1 K: 8 M: 1 F: 2 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 6
Chemical Descriptors
46
C213H365N59O60S3
4808.78
10.11
+5
11.24
0.215
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
4.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
2.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
4.1 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
4.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
2.1 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
4.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
4.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
2.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
4.1 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
4.1 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 4.1 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
2.1 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.2 ug/ml), Gram+ bacteria S. aureus (MIC 4.1 ug/ml), and yeast C. albicans (MIC 2.1 ug/ml). Updated 7/2021