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Peptide record

TPDB12132

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12132
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFSKISGKAIKNLFIKGAENVGKHVGIDVVRTGIDVVGCKIKGEC
Physicochemical Analysis
C214H362N60O60S2
QMPWY
G
4799.71
9.91
9
4
18
+4
11.13
0.287
110.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.60
7
Residue Composition
number
2
A
1
R
2
N
2
D
2
C
2
E
0
Q
8
G
1
H
7
I
1
L
7
K
0
M
2
F
0
P
2
S
1
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 2 C: 2 E: 2 Q: 0 G: 8 H: 1 I: 7 L: 1 K: 7 M: 0 F: 2 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 6
Chemical Descriptors
46
C214H362N60O60S2
4799.71
9.91
+4
11.13
0.287
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
8.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

(MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
8.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
8.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
8.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
8.6 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
8.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
8.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
8.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
8.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
8.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

(MIC 8.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
8.6 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 8.6 ug/ml), Gram+ bacteria S. aureus (MIC 8.6 ug/ml), and yeast C. albicans (MIC 8.6 ug/ml). Updated 7/2021