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Peptide record

TPDB12125

Antibacterial Antifungal Antiparasitic Hemolysis Toxicity standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12125
Antibacterial Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP dbAMP 3.0 PD_Hemolysis
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FFFHIVKGLFHAGRMIHGLVNRRRHRHGMEELDLDQRAFEREKAFA
Physicochemical Analysis
C251H385N81O61S2
CPSTWY
R
5577.44
11.17
14
6
20
+3
13.39
-0.533
72.17
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
7
R
1
N
2
D
0
C
4
E
1
Q
4
G
5
H
2
I
4
L
2
K
2
M
6
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 7 N: 1 D: 2 C: 0 E: 4 Q: 1 G: 4 H: 5 I: 2 L: 4 K: 2 M: 2 F: 6 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
46
C251H385N81O61S2
5577.44
11.17
+3
13.39
-0.533
Evidence Records 5 records
Evidence 1 Activity

Activity

4.03±0.31% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
4.03±0.31% Hemolysis | 2.5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 2 Activity

Activity

7.73±0.69% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
7.73±0.69% Hemolysis | 5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 3 Activity

Activity

15.56±1.05% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
15.56±1.05% Hemolysis | 10 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 4 Activity

Activity

23.73±2.69% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
23.73±2.69% Hemolysis | 20 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis