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Peptide record

TPDB12105

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB12105
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
QQCGRQAGNRRCANNLCCSQYGYCGRTNEYCCTSQGCQSQCRRCG
Physicochemical Analysis
C190H306N74O67S10
DHIKMFPWV
C
5019.58
8.31
6
1
6
+5
7.23
-1.038
13.11
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5095
101.50
29
Residue Composition
number
2
A
6
R
4
N
0
D
10
C
1
E
7
Q
6
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
3
S
2
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 4 D: 0 C: 10 E: 1 Q: 7 G: 6 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 3 T: 2 W: 0 Y: 3 V: 0
Chemical Descriptors
45
C190H306N74O67S10
5019.58
8.31
+5
7.23
-1.038
Evidence Records 12 records
Evidence 1 Activity

Activity

IC50
Antibacterial
15 µg/mL

Target

p.cubense

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
wth inhibition IC50 3 ug/ml), B. cinerea (1 ug/ml), F. culmorum (3 ug/ml), F. oxysporumf.sp.cubense (IC50 15 ug/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. ex
Evidence 2 Activity

Activity

IC50
Antibacterial
33 µg/mL

Target

P. exigua

Source & Reference

dbAMP DRAMP

Other

g/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. exigua (IC50 33 ug/ml), P. cryptogea (25 ug/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug
Evidence 3 Activity

Activity

IC50
Antibacterial
2 µg/mL

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug/ml), Gram+ bacteria B. megaterium (IC50 2 ug/ml) and S. luted (7 ug/ml). These microtiterplate assay results are comparable to those from
Evidence 4 Activity

Activity

IC50
Antifungal
15 µg/mL

Target

p.cubense

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
wth inhibition IC50 3 ug/ml), B. cinerea (1 ug/ml), F. culmorum (3 ug/ml), F. oxysporumf.sp.cubense (IC50 15 ug/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. ex
Evidence 5 Activity

Activity

IC50
Antifungal
33 µg/mL

Target

P. exigua

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. exigua (IC50 33 ug/ml), P. cryptogea (25 ug/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug
Evidence 6 Activity

Activity

IC50
Antifungal
2 µg/mL

Target

B. megaterium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug/ml), Gram+ bacteria B. megaterium (IC50 2 ug/ml) and S. luted (7 ug/ml). These microtiterplate assay results are comparable to those from
Evidence 7 Activity

Activity

IC50
Antiparasitic
15 µg/mL

Target

p.cubense

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
wth inhibition IC50 3 ug/ml), B. cinerea (1 ug/ml), F. culmorum (3 ug/ml), F. oxysporumf.sp.cubense (IC50 15 ug/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. ex
Evidence 8 Activity

Activity

IC50
Antiparasitic
33 µg/mL

Target

P. exigua

Source & Reference

DRAMP

Other

g/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. exigua (IC50 33 ug/ml), P. cryptogea (25 ug/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug
Evidence 9 Activity

Activity

IC50
Antiparasitic
2 µg/mL

Target

B. megaterium

Source & Reference

DRAMP

Other

/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug/ml), Gram+ bacteria B. megaterium (IC50 2 ug/ml) and S. luted (7 ug/ml). These microtiterplate assay results are comparable to those from
Evidence 10 Activity

Activity

IC50
Antiviral
15 µg/mL

Target

p.cubense

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
wth inhibition IC50 3 ug/ml), B. cinerea (1 ug/ml), F. culmorum (3 ug/ml), F. oxysporumf.sp.cubense (IC50 15 ug/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. ex
Evidence 11 Activity

Activity

IC50
Antiviral
33 µg/mL

Target

P. exigua

Source & Reference

DRAMP

Other

g/ml), F. oxysporumf.sp. matthiolae (5 ug/ml), M. eumusae (6 ug/ml), N. crassa (2 ug/ml), P. exigua (IC50 33 ug/ml), P. cryptogea (25 ug/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug
Evidence 12 Activity

Activity

IC50
Antiviral
2 µg/mL

Target

B. megaterium

Source & Reference

DRAMP

Other

/ml), P. ultimum (33 ug/ml), R. solani (25 ug/ml), T. hamatum (100 ug/ml), Gram+ bacteria B. megaterium (IC50 2 ug/ml) and S. luted (7 ug/ml). These microtiterplate assay results are comparable to those from