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Peptide record

TPDB12101

Antibacterial Hemolysis Toxicity standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB12101
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GIINTLQKYYWRVRGGRWAVLSWLPKEEQIGKWSTRGRKWWRRKK
Physicochemical Analysis
C264H407N81O59
DCHMF
R
5659.64
12.06
13
2
17
+11
2.65
-1.153
67.11
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
35980
635.73
9
Residue Composition
number
1
A
7
R
1
N
0
D
0
C
2
E
2
Q
5
G
0
H
3
I
3
L
6
K
0
M
0
F
1
P
2
S
2
T
6
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 0 E: 2 Q: 2 G: 5 H: 0 I: 3 L: 3 K: 6 M: 0 F: 0 P: 1 S: 2 T: 2 W: 6 Y: 2 V: 2
Chemical Descriptors
45
C264H407N81O59
5659.64
12.06
+11
2.65
-1.153
Evidence Records 3 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 50 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Linear analogues of human beta-defensin 3: concepts for design of antimicrobial peptides with reduced cytotoxicity to mammalian cells. | Chembiochem | 2008
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Linear analogues of human beta-defensin 3: concepts for design of antimicrobial peptides with reduced cytotoxicity to mammalian cells. | Chembiochem | 2008
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis