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Peptide record

TPDB12095

Antibacterial Antifungal standard
45 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12095
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 45-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
SMATPHVAGAAALILSKHPTWTNAQVRDRLESTATYLGNSFYYGK
Physicochemical Analysis
C219H337N61O65S1
C
A
4896.51
9.82
6
2
20
+2
2.71
-0.249
71.78
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
9970
203.61
15
Residue Composition
number
7
A
2
R
2
N
1
D
0
C
1
E
1
Q
3
G
2
H
1
I
4
L
2
K
1
M
1
F
2
P
4
S
5
T
1
W
3
Y
2
V
Amino Acid Distribution
A: 7 R: 2 N: 2 D: 1 C: 0 E: 1 Q: 1 G: 3 H: 2 I: 1 L: 4 K: 2 M: 1 F: 1 P: 2 S: 4 T: 5 W: 1 Y: 3 V: 2
Chemical Descriptors
45
C219H337N61O65S1
4896.51
9.82
+2
2.71
-0.249
Evidence Records 40 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

B.cereus JCM 2152T or AHU 1358

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram+ B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumi
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

B. licheniformis AHU 1371

Source & Reference

dbAMP

Other

Active against Gram+ B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

B.megaterium AHU 1373

Source & Reference

dbAMP

Other

B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s
Evidence 4 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

B. pumilus AHU 1386

Source & Reference

dbAMP

Other

ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L.
Evidence 5 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

(MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.p
Evidence 6 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

Enterococcus faecalis s strains HU1 VRE

Source & Reference

dbAMP

Other

C >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnos
Evidence 7 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

L. fermentum ATCC 9338

Source & Reference

dbAMP

Other

l), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aure
Evidence 8 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

L.plantarum NRIC 1067T

Source & Reference

dbAMP

Other

ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (M
Evidence 9 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.aureus ATCC 25923 MRSA-inactive

Source & Reference

dbAMP

Other

ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JC
Evidence 10 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Streptococcus agalactiae JCM 5671T

Source & Reference

dbAMP

Other

TCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae AT
Evidence 11 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. mitis JCM 12971T

Source & Reference

dbAMP

Other

CC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/
Evidence 12 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. mutans JCM 5705T

Source & Reference

dbAMP

Other

C>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 u
Evidence 13 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

S. pneumoniae ATCC 49619 and

Source & Reference

dbAMP

Other

T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguin
Evidence 14 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.pyogenes JCM 5674T

Source & Reference

dbAMP

Other

mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.b
Evidence 15 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.salivarius JCM 5707T

Source & Reference

dbAMP

Other

eumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128
Evidence 16 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. sanguinis JCM 5708T

Source & Reference

dbAMP

Other

-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains
Evidence 17 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

A.baumannii ATCC 19606T or SRAC2

Source & Reference

dbAMP

Other

ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml)
Evidence 18 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

E.coli ATCC 25922 and

Source & Reference

dbAMP

Other

guinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marc
Evidence 19 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

H.infuenza ATCC 51907

Source & Reference

dbAMP

Other

ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marcescens SRSM2 (MIC > 128 ug/ml), fungi C.
Evidence 20 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

P.aeruginosa ATCC 27853

Source & Reference

dbAMP

Other

E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marcescens SRSM2 (MIC > 128 ug/ml), fungi C.albicans SRCA1 (MIC > 128 ug/ml). Addition
Evidence 21 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

B.cereus JCM 2152T or AHU 1358

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram+ B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumi
Evidence 22 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

B. licheniformis AHU 1371

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram+ B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6
Evidence 23 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

B.megaterium AHU 1373

Source & Reference

dbAMP CAFPdb Antifungipept

Other

B.cereus JCM 2152T or AHU 1358 (MIC>128 ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s
Evidence 24 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

B. pumilus AHU 1386

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), B. licheniformis AHU 1371 (MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L.
Evidence 25 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 8 ug/ml), B.megaterium AHU 1373 (MIC >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.p
Evidence 26 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

Enterococcus faecalis s strains HU1 VRE

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C >128 ug/ml), B. pumilus AHU 1386 (MIC 8 ug/ml), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnos
Evidence 27 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

L. fermentum ATCC 9338

Source & Reference

dbAMP CAFPdb Antifungipept

Other

l), B. subtilis 6 strains (MIC 8-16 ug/ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aure
Evidence 28 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

L.plantarum NRIC 1067T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ml), E.faecalis s strains HU1 VRE (MIC>128 ug/ml), L. fermentum ATCC 9338 (MIC 64 ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (M
Evidence 29 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

S.aureus ATCC 25923 MRSA-inactive

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), L.plantarum NRIC 1067T (MIC>128 ug/ml), L.rhamnosus ATCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JC
Evidence 30 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Streptococcus agalactiae JCM 5671T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

TCC 7469T (MIC > 128 ug/ml), S.aureus ATCC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae AT
Evidence 31 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. mitis JCM 12971T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

CC 25923 3 strains MRSA-inactive (MIC>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/
Evidence 32 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. mutans JCM 5705T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C>128 ug/ml), S. agalactiae JCM 5671T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 u
Evidence 33 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

S. pneumoniae ATCC 49619 and

Source & Reference

dbAMP CAFPdb Antifungipept

Other

T (MIC 64 ug/ml), S. mitis JCM 12971T (MIC 64 ug/ml), S. mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguin
Evidence 34 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

S.pyogenes JCM 5674T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

mutans JCM 5705T (MIC 64 ug/ml), S. pneumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.b
Evidence 35 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

S.salivarius JCM 5707T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

eumoniae ATCC 49619 and 6 strains (MIC 8-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128
Evidence 36 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. sanguinis JCM 5708T

Source & Reference

dbAMP CAFPdb Antifungipept

Other

-16 ug/ml), S.pyogenes JCM 5674T (MIC 128 ug/ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains
Evidence 37 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

A.baumannii ATCC 19606T or SRAC2

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ml), S.salivarius JCM 5707T (MIC 128 ug/ml), S. sanguinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml)
Evidence 38 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

E.coli ATCC 25922 and

Source & Reference

dbAMP CAFPdb Antifungipept

Other

guinis JCM 5708T (MIC 64 ug/ml), Gram- A.baumannii ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marc
Evidence 39 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

H.infuenza ATCC 51907

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ATCC 19606T or SRAC2 (MIC >128 ug/ml), E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marcescens SRSM2 (MIC > 128 ug/ml), fungi C.
Evidence 40 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

P.aeruginosa ATCC 27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

E.coli ATCC 25922 and 2 strains (MIC >128 ug/ml), H.infuenza ATCC 51907 (MIC >128 ug/ml), P.aeruginosa ATCC 27853 (MIC >128 ug/ml), S.marcescens SRSM2 (MIC > 128 ug/ml), fungi C.albicans SRCA1 (MIC > 128 ug/ml). Addition