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Peptide record

TPDB12071

Antibacterial Antifungal Toxicity standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB12071
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GASPALWGCDSFLGYCRIACFAHEASVGQKDCAEGMICCLPNVF
Physicochemical Analysis
C202H303N53O59S7
T
AC
4642.37
4.54
3
4
19
-2
0.57
0.511
71.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
158.65
12
Residue Composition
number
6
A
1
R
1
N
2
D
6
C
2
E
1
Q
5
G
1
H
2
I
3
L
1
K
1
M
3
F
2
P
3
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 6 R: 1 N: 1 D: 2 C: 6 E: 2 Q: 1 G: 5 H: 1 I: 2 L: 3 K: 1 M: 1 F: 3 P: 2 S: 3 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
44
C202H303N53O59S7
4642.37
4.54
-2
0.57
0.511
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
19.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
17.3 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
38.8 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
43.1 µM

Target

B. subtilis

Source & Reference

NA

Other

against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
19.4 µM

Target

Pseudomonas aeruginosa

Source & Reference

Antifungipept

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
17.3 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
38.8 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
43.1 µM

Target

B. subtilis

Source & Reference

Antifungipept

Other

against P. aeruginosa (MIC 19.4 uM), S. aureus (MIC 17.3 uM), E. coli (MIC 38.8 uM), and B. subtilis (MIC 43.1 uM).
Evidence 9 Activity

Activity

4% Hemolysis
Toxicity
43.14 µM
Hemolytic Cytotoxic
4% Hemolysis | 43.14 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The first anionic defensin from amphibians. | Amino Acids | 2015