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Peptide record

TPDB12068

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB12068
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRY
Physicochemical Analysis
C219H336N66O61S6
ADEHKMW
RC
5061.84
9.16
6
0
13
+6
-0.89
-0.334
48.64
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
7825
154.59
22
Residue Composition
number
0
A
6
R
1
N
0
D
6
C
0
E
3
Q
5
G
0
H
1
I
3
L
0
K
0
M
2
F
3
P
4
S
3
T
0
W
5
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 6 E: 0 Q: 3 G: 5 H: 0 I: 1 L: 3 K: 0 M: 0 F: 2 P: 3 S: 4 T: 3 W: 0 Y: 5 V: 2
Chemical Descriptors
44
C219H336N66O61S6
5061.84
9.16
+6
-0.89
-0.334
Evidence Records 13 records
Evidence 1 Activity

Activity

IC50
Antibacterial
25 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml
Evidence 2 Activity

Activity

IC50
Antibacterial
4.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 3 Activity

Activity

IC50
Antibacterial
3.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 4 Activity

Activity

IC50
Antibacterial
0.5 µg/mL

Target

P. pastoris

Source & Reference

dbAMP DRAMP

Other

nst E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 5 Activity

Activity

IC50
Antifungal
25 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml
Evidence 6 Activity

Activity

IC50
Antifungal
4.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 7 Activity

Activity

IC50
Antifungal
3.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 8 Activity

Activity

IC50
Antifungal
0.5 µg/mL

Target

P. pastoris

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

nst E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 9 Activity

Activity

IC50
Antiparasitic
25 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml
Evidence 10 Activity

Activity

IC50
Antiparasitic
4.2 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 11 Activity

Activity

IC50
Antiparasitic
3.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

Active against E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 12 Activity

Activity

IC50
Antiparasitic
0.5 µg/mL

Target

P. pastoris

Source & Reference

DRAMP

Other

nst E. coli (IC50 25 ug/ml), S. aureus (IC50 4.2 ug/ml), C. albicans (IC50 3.0 ug/ml) and P. pastoris (IC50 0.5 ug/ml).
Evidence 13 Activity

Activity

0% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
0% Hemolysis | 10 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP