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Peptide record

TPDB12064

Antibacterial Antifungal Hemolysis Toxicity standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB12064
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifp Antifungipept APD_complete HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifp, and other sources, with an available 3D structural model.
Sequence
MVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Physicochemical Analysis
C233H409N59O56S3
DCHPWY
L
5029.35
11.53
7
2
26
+5
0.95
1.009
168.41
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
2
A
3
R
1
N
0
D
0
C
2
E
1
Q
2
G
0
H
6
I
11
L
4
K
3
M
2
F
0
P
3
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 2 H: 0 I: 6 L: 11 K: 4 M: 3 F: 2 P: 0 S: 3 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
44
C233H409N59O56S3
5029.35
11.53
+5
0.95
1.009
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Dual toxic-peptide-coding Staphylococcus aureus RNA under antisense regulation targets host cells and bacterial rivals unequally. | Cell Rep | 2014
Evidence 2 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.