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Peptide record

TPDB12054

Antibacterial Hemolysis Toxicity standard
44 amino acids
Basic Information
3D PDB MODEL
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TPDB12054
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 44-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RPPQFTRAQWFAIQHISLNPPRSTIAMRAINNYRWRSKNQNTFL
Physicochemical Analysis
C240H370N76O61S1
DCEGV
R
5328.11
12.70
8
0
17
+7
2.54
-0.830
62.27
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12490
234.42
16
Residue Composition
number
4
A
6
R
5
N
0
D
0
C
0
E
4
Q
0
G
1
H
4
I
2
L
1
K
1
M
3
F
4
P
3
S
3
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 4 R: 6 N: 5 D: 0 C: 0 E: 0 Q: 4 G: 0 H: 1 I: 4 L: 2 K: 1 M: 1 F: 3 P: 4 S: 3 T: 3 W: 2 Y: 1 V: 0
Chemical Descriptors
44
C240H370N76O61S1
5328.11
12.70
+7
2.54
-0.830
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
9.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 9.5 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus. | Biochem J | 2013
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis