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Peptide record

TPDB12032

Antibacterial Antifungal standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12032
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 43-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
MSDNKPDISDVTSFDKTKLKKTETQEKNTLPTKEIEQEKSESS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C207H345N55O80S1
ARCGHWY
K
4916.40
4.72
8
10
7
-2
3.52
-1.556
43.02
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
16
Residue Composition
number
0
A
0
R
2
N
4
D
0
C
6
E
2
Q
0
G
0
H
2
I
2
L
8
K
1
M
1
F
2
P
6
S
6
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 4 C: 0 E: 6 Q: 2 G: 0 H: 0 I: 2 L: 2 K: 8 M: 1 F: 1 P: 2 S: 6 T: 6 W: 0 Y: 0 V: 1
Chemical Descriptors
43 reviewed residue count
C207H345N55O80S1 sequence-only estimate (linear, free termini)
4916.40 sequence-only estimate (linear, free termini)
4.72 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
3.52 sequence-only estimate (linear, free termini)
-1.556 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram- E. tarda, V. harveyi (a bioluminescent marine bacterium), and Gram+ S. agalactiae (also known as group B streptococcus or GBS). In addition, it is involved in antibacterial immune response.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against Gram- E. tarda, V. harveyi (a bioluminescent marine bacterium), and Gram+ S. agalactiae (also known as group B streptococcus or GBS). In addition, it is involved in antibacterial immune response.