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Peptide record

TPDB12027

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12027
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept AI4AVP dbAMP 3.0
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLRKKFRKTRKRIQKLGRKIGKTGRKVWKAWREYGQIPYPCRI
Physicochemical Analysis
C241H404N80O52S1
NDHMS
K
5286.42
12.22
17
1
13
+16
10.39
-1.295
63.49
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
13980
264.45
7
Residue Composition
number
1
A
8
R
0
N
0
D
1
C
1
E
2
Q
5
G
0
H
4
I
2
L
9
K
0
M
1
F
2
P
0
S
2
T
2
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 8 N: 0 D: 0 C: 1 E: 1 Q: 2 G: 5 H: 0 I: 4 L: 2 K: 9 M: 0 F: 1 P: 2 S: 0 T: 2 W: 2 Y: 2 V: 1
Chemical Descriptors
43
C241H404N80O52S1
5286.42
12.22
+16
10.39
-1.295
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli and S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli and S. aureus.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
active against E. coli and S. aureus.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
active against E. coli and S. aureus.
Evidence 5 Activity

Activity

4% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 64 | µg/mL | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Comparative Evaluation of the Antimicrobial Activity of Different Antimicrobial Peptides against a Range of Pathogenic Bacteria. | PLoS One | 2015