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Peptide record

TPDB12026

Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12026
Anti-inflammatory Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Immunity and inflammation peptides Toxicity and safety peptides
Peptipedia AntiBP3 dbAMP AFP-GFuse Antifungipept CAFPdb
standard
No
A 43-aa standard natural multi-activity (Anti-inflammatory, Antibacterial, Anticancer, and other sources) peptide sequence curated from Peptipedia, AntiBP3, dbAMP, and other sources, with an available 3D structural model.
Sequence
VTCDVLSFEAKGIAVNHSACALHCIALRKKGGSCQNGVCVCRN
Physicochemical Analysis
C186H312N60O56S6
MPWY
C
4477.25
8.32
7
2
16
+3
6.80
0.358
90.70
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
375
8.38
14
Residue Composition
number
5
A
2
R
3
N
1
D
6
C
1
E
1
Q
4
G
2
H
2
I
3
L
3
K
0
M
1
F
0
P
3
S
1
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 5 R: 2 N: 3 D: 1 C: 6 E: 1 Q: 1 G: 4 H: 2 I: 2 L: 3 K: 3 M: 0 F: 1 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 5
Chemical Descriptors
43
C186H312N60O56S6
4477.25
8.32
+3
6.80
0.358
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against multiple fungi with MIC 5-20 uM. CopN1, with 43 residues, is active against E. coli and S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against multiple fungi with MIC 5-20 uM. CopN1, with 43 residues, is active against E. coli and S. aureus.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

Active against multiple fungi with MIC 5-20 uM. CopN1, with 43 residues, is active against E. coli and S. aureus.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

NA

Other

Active against multiple fungi with MIC 5-20 uM. CopN1, with 43 residues, is active against E. coli and S. aureus.
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Insight into the antimicrobial activities of coprisin isolated from the dung beetle, Copris tripartitus, revealed by structure-activity relationships | Biochim Biophys Acta | 2013