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Peptide record

TPDB12025

Antibacterial Anticancer Antifungal Antiparasitic standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12025
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
TKYYGNGVYCNSKKCWVDWGTAQGCIDVVIGQLGGGIPGKGKC
Physicochemical Analysis
C200H308N54O58S4
REHMF
G
4525.21
8.66
5
2
14
+3
1.51
-0.188
65.58
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
15720
347.39
14
Residue Composition
number
1
A
0
R
2
N
2
D
4
C
0
E
2
Q
10
G
0
H
3
I
1
L
5
K
0
M
0
F
1
P
1
S
2
T
2
W
3
Y
4
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 2 C: 4 E: 0 Q: 2 G: 10 H: 0 I: 3 L: 1 K: 5 M: 0 F: 0 P: 1 S: 1 T: 2 W: 2 Y: 3 V: 4
Chemical Descriptors
43
C200H308N54O58S4
4525.21
8.66
+3
1.51
-0.188
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
characterized by high antilisterial activity. Of 24 tested strains of L. monocytogenes, 22 appeared to be sensitive to divergicin M35 (inhibition zone diameter: 10-22 mm). Also active against Carnobacterium spp. but inactive against L.lactis, subsp. l.biovar. diacetylatis UL719, P.acidilactici, P.pentosaceus, L.plantarum, L.acidophilus, L.salivarius, L.casei, L.rhamnosus, S.thermophilus, Propionibacterium spp., P.freudenreichii, B. breveand P.acidilactici UL5, E.coli. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
characterized by high antilisterial activity. Of 24 tested strains of L. monocytogenes, 22 appeared to be sensitive to divergicin M35 (inhibition zone diameter: 10-22 mm). Also active against Carnobacterium spp. but inactive against L.lactis, subsp. l.biovar. diacetylatis UL719, P.acidilactici, P.pentosaceus, L.plantarum, L.acidophilus, L.salivarius, L.casei, L.rhamnosus, S.thermophilus, Propionibacterium spp., P.freudenreichii, B. breveand P.acidilactici UL5, E.coli. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

characterized by high antilisterial activity. Of 24 tested strains of L. monocytogenes, 22 appeared to be sensitive to divergicin M35 (inhibition zone diameter: 10-22 mm). Also active against Carnobacterium spp. but inactive against L.lactis, subsp. l.biovar. diacetylatis UL719, P.acidilactici, P.pentosaceus, L.plantarum, L.acidophilus, L.salivarius, L.casei, L.rhamnosus, S.thermophilus, Propionibacterium spp., P.freudenreichii, B. breveand P.acidilactici UL5, E.coli. Updated 7/2021