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Peptide record

TPDB12023

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12023
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCPGNQLKCNNHCKSISCRAGYCDAATLWLRCTCTDCNGKK
Physicochemical Analysis
C190H303N61O59S8
EMV
C
4642.35
8.31
7
2
10
+4
4.10
-0.412
43.26
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7490
161.34
19
Residue Composition
number
3
A
2
R
4
N
2
D
8
C
0
E
1
Q
5
G
1
H
1
I
3
L
4
K
0
M
1
F
1
P
2
S
3
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 4 D: 2 C: 8 E: 0 Q: 1 G: 5 H: 1 I: 1 L: 3 K: 4 M: 0 F: 1 P: 1 S: 2 T: 3 W: 1 Y: 1 V: 0
Chemical Descriptors
43
C190H303N61O59S8
4642.35
8.31
+4
4.10
-0.412
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.01-2 µM

Target

B. stationis CIP 101282

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
CIP 103428, S. aureus SG511, S. simulans 22, S. hemolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µM

Target

Escherichia coli SBS 363

Source & Reference

dbAMP DRAMP

Other

emolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).
Evidence 3 Activity

Activity

MIC
Antifungal
0.01-2 µM

Target

B. stationis CIP 101282

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
CIP 103428, S. aureus SG511, S. simulans 22, S. hemolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
20 µM

Target

Escherichia coli SBS 363

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

emolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).
Evidence 5 Activity

Activity

MIC
Antiparasitic
0.01-2 µM

Target

B. stationis CIP 101282

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
CIP 103428, S. aureus SG511, S. simulans 22, S. hemolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).
Evidence 6 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Escherichia coli SBS 363

Source & Reference

DRAMP

Other

emolyticus, M. maritypicum CIP 105733T, B. stationis CIP 101282 (MIC 0.01-2 uM),and Gram- E. coli SBS 363 (MIC 20 uM).