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Peptide record

TPDB12020

Antibacterial Anticancer Antifungal Antiparasitic standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12020
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ATCDILSFQSQWVTPNHAGCALHCVIKGYKGGQCKITVCHCRR
Physicochemical Analysis
C203H323N63O56S6
EM
C
4734.55
8.59
8
1
14
+4
4.32
-0.000
72.56
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
7365
155.56
16
Residue Composition
number
3
A
2
R
1
N
1
D
6
C
0
E
3
Q
4
G
3
H
3
I
2
L
3
K
0
M
1
F
1
P
2
S
3
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 1 C: 6 E: 0 Q: 3 G: 4 H: 3 I: 3 L: 2 K: 3 M: 0 F: 1 P: 1 S: 2 T: 3 W: 1 Y: 1 V: 3
Chemical Descriptors
43
C203H323N63O56S6
4734.55
8.59
+4
4.32
-0.000
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.15-0.3 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2
Evidence 2 Activity

Activity

MIC
Antibacterial
0.3-0.6 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2
Evidence 3 Activity

Activity

MIC
Antibacterial
0.62-1.25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (M
Evidence 4 Activity

Activity

MIC
Antibacterial
1.25-2.5 µM

Target

S. saprophyticus

Source & Reference

dbAMP DRAMP

Other

megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5
Evidence 5 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

P. acidilactici

Source & Reference

dbAMP DRAMP

Other

idans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

B. subtilis QB935

Source & Reference

dbAMP DRAMP

Other

s (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 7 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

Escherichia coli D22

Source & Reference

dbAMP DRAMP

Other

icus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
0.15-0.3 µM

Target

B. megaterium

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2
Evidence 9 Activity

Activity

MIC
Antifungal
0.3-0.6 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2
Evidence 10 Activity

Activity

MIC
Antifungal
0.62-1.25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (M
Evidence 11 Activity

Activity

MIC
Antifungal
1.25-2.5 µM

Target

S. saprophyticus

Source & Reference

dbAMP DRAMP

Other

megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5
Evidence 12 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

P. acidilactici

Source & Reference

dbAMP DRAMP

Other

idans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

B. subtilis QB935

Source & Reference

dbAMP DRAMP

Other

s (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 14 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

Escherichia coli D22

Source & Reference

dbAMP DRAMP

Other

icus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 15 Activity

Activity

MIC
Antiparasitic
0.15-0.3 µM

Target

B. megaterium

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2
Evidence 16 Activity

Activity

MIC
Antiparasitic
0.3-0.6 µM

Target

A. viridans

Source & Reference

DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2
Evidence 17 Activity

Activity

MIC
Antiparasitic
0.62-1.25 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

Active against M. luteus, B. megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (M
Evidence 18 Activity

Activity

MIC
Antiparasitic
1.25-2.5 µM

Target

S. saprophyticus

Source & Reference

DRAMP

Other

megaterium (MIC 0.15-0.3 uM), A. viridans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5
Evidence 19 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

P. acidilactici

Source & Reference

DRAMP

Other

idans (MIC 0.3-0.6 uM), S. aureus (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 20 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

B. subtilis QB935

Source & Reference

DRAMP

Other

s (MIC 0.62-1.25 uM), S. saprophyticus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).
Evidence 21 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

Escherichia coli D22

Source & Reference

DRAMP

Other

icus (MIC 1.25-2.5 uM), P. acidilactici (MIC 2.5-5 uM), B. subtilis QB935 (MIC 2.5-5 uM), E. coli D22 (MIC 2.5-5 uM).