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Peptide record

TPDB12013

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12013
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept CAFPdb
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
DRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKLYEEDDMF
Physicochemical Analysis
C217H356N64O71S7
ANHWV
C
5222.02
6.32
10
10
10
-0
19.54
-1.012
54.42
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
3355
64.25
13
Residue Composition
number
0
A
5
R
0
N
5
D
6
C
5
E
1
Q
1
G
0
H
3
I
3
L
5
K
1
M
1
F
1
P
2
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 5 C: 6 E: 5 Q: 1 G: 1 H: 0 I: 3 L: 3 K: 5 M: 1 F: 1 P: 1 S: 2 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
43
C217H356N64O71S7
5222.02
6.32
-0
19.54
-1.012
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The novel human ?-defensin 114 regulates lipopolysaccharide (LPS)-mediated inflammation and protects sperm from motility loss. | J Biol Chem | 2013