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Peptide record

TPDB12009

Antibacterial Hemolysis Toxicity standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12009
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KKKKKKKKKKKKKKKKKKKKGIGKFLHSAKKFGKAFVGEIMNS
Physicochemical Analysis
C234H420N70O49S1
RDCQPTWY
K
5030.41
11.54
25
1
10
+23
22.39
-1.770
38.60
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
24
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 24 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
43
C234H420N70O49S1
5030.41
11.54
+23
22.39
-1.770
Evidence Records 3 records
Evidence 1 Activity

Activity

6% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
6% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 2 Activity

Activity

14% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
14% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Augmentation of the antibacterial activity of magainin by positive-charge chain extension. | Antimicrob Agents Chemother | 1992
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis