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Peptide record

TPDB12008

Antibacterial Antifungal standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB12008
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 43-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VSFPWSCAALSGVCRQGACLPSELYFGPLGCGKGSLCCVSYFL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C201H303N49O55S6
NDHIMT
CGLS
4478.27
7.62
2
1
18
+1
-0.42
0.774
81.63
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
8855
1.98
15
Residue Composition
number
3
A
1
R
0
N
0
D
6
C
1
E
1
Q
6
G
0
H
0
I
6
L
1
K
0
M
3
F
3
P
6
S
0
T
1
W
2
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 6 E: 1 Q: 1 G: 6 H: 0 I: 0 L: 6 K: 1 M: 0 F: 3 P: 3 S: 6 T: 0 W: 1 Y: 2 V: 3
Chemical Descriptors
43 reviewed residue count
C201H303N49O55S6 sequence-only estimate (linear, free termini)
4478.27 sequence-only estimate (linear, free termini)
7.62 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
-0.42 sequence-only estimate (linear, free termini)
0.774 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5-25 µg/mL

Target

Streptococcus agalactiae

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
coli, E. ictaluri, Y. ruckeri, A. hydrophila, A. veronii, Gram+ S. aureus, S. iniae, and S. agalactiae (MIC 12.5-25 ug/ml). Activity was also demonstrated by inhibition zone measurements (8.6-19.2 mm).
Evidence 2 Activity

Activity

MIC
Antifungal
12.5-25 µg/mL

Target

Streptococcus agalactiae

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
coli, E. ictaluri, Y. ruckeri, A. hydrophila, A. veronii, Gram+ S. aureus, S. iniae, and S. agalactiae (MIC 12.5-25 ug/ml). Activity was also demonstrated by inhibition zone measurements (8.6-19.2 mm).