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Peptide record

TPDB12001

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
43 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12001
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifp Antifungipept CAFPdb
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RFRPPIRRPPIRPPFYPPFRPPIRPPIFPPIRPPFRPPLGPFP
Physicochemical Analysis
C255H382N70O45
ANDCEQHKMSTWV
P
5148.28
12.94
9
0
13
+9
6.47
-0.723
54.42
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
28.94
1
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
5
I
1
L
0
K
0
M
6
F
20
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 5 L: 1 K: 0 M: 0 F: 6 P: 20 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
43
C255H382N70O45
5148.28
12.94
+9
6.47
-0.723
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC
Evidence 2 Activity

Activity

MIC
Antibacterial
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provi
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP

Other

5922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13
Evidence 4 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

dbAMP DRAMP

Other

imurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 770
Evidence 5 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

P.vulgaris ATCC 13315

Source & Reference

dbAMP DRAMP

Other

883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus
Evidence 6 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

P.aeruginosa ATCC 7700

Source & Reference

dbAMP DRAMP

Other

13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalac
Evidence 7 Activity

Activity

MIC
Antibacterial
>200 µM

Target

S.epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP

Other

eng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments
Evidence 8 Activity

Activity

MIC
Antibacterial
>200 µg/mL

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

00 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments of Bac5 was generated to identify the
Evidence 9 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC
Evidence 10 Activity

Activity

MIC
Antifungal
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provi
Evidence 11 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

5922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13
Evidence 12 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

imurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 770
Evidence 13 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

P.vulgaris ATCC 13315

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus
Evidence 14 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

P.aeruginosa ATCC 7700

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalac
Evidence 15 Activity

Activity

MIC
Antifungal
>200 µM

Target

S.epidermidis ATCC 12228

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

eng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments
Evidence 16 Activity

Activity

MIC
Antifungal
>200 µg/mL

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

00 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments of Bac5 was generated to identify the
Evidence 17 Activity

Activity

MIC
Antiparasitic
12 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC
Evidence 18 Activity

Activity

MIC
Antiparasitic
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provi
Evidence 19 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

5922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13
Evidence 20 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

DRAMP

Other

imurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 770
Evidence 21 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

P.vulgaris ATCC 13315

Source & Reference

DRAMP

Other

883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus
Evidence 22 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

P.aeruginosa ATCC 7700

Source & Reference

DRAMP

Other

13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalac
Evidence 23 Activity

Activity

MIC
Antiparasitic
>200 µM

Target

S.epidermidis ATCC 12228

Source & Reference

DRAMP

Other

eng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments
Evidence 24 Activity

Activity

MIC
Antiparasitic
>200 µg/mL

Target

S.aureus ATCC 25923

Source & Reference

DRAMP

Other

00 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments of Bac5 was generated to identify the
Evidence 25 Activity

Activity

MIC
Antiviral
12 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC
Evidence 26 Activity

Activity

MIC
Antiviral
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provi
Evidence 27 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

5922 (MIC 12 ug/ml), S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13
Evidence 28 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

DRAMP

Other

imurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 770
Evidence 29 Activity

Activity

MIC
Antiviral
>200 µg/mL

Target

P.vulgaris ATCC 13315

Source & Reference

DRAMP

Other

883 (MIC 25 ug/ml), and E. cloacae ATCC 13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus
Evidence 30 Activity

Activity

MIC
Antiviral
>200 µg/mL

Target

P.aeruginosa ATCC 7700

Source & Reference

DRAMP

Other

13047 (MIC 25 ug/ml) (provided by Chunfeng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalac
Evidence 31 Activity

Activity

MIC
Antiviral
>200 µM

Target

S.epidermidis ATCC 12228

Source & Reference

DRAMP

Other

eng Wang), P.vulgaris ATCC 13315 (MIC>200 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments
Evidence 32 Activity

Activity

MIC
Antiviral
>200 µg/mL

Target

S.aureus ATCC 25923

Source & Reference

DRAMP

Other

00 ug/ml), P.aeruginosa ATCC 7700 (MIC>200 ug/ml), S.epidermidis ATCC 12228 (MIC>200 uM), S.aureus ATCC 25923 (MIC>200 ug/ml), and S.agalactiae (MIC > 200 ug/ml). SAR: Fragments of Bac5 was generated to identify the