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Peptide record

TPDB11997

Antibacterial Anticancer Antifungal Antiparasitic standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB11997
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept CAFPdb
standard
No
A 43-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
VTCDILSVEAKGVKLNDAACAAHCLFRGRSGGYCNGKRVCVCR
Physicochemical Analysis
C189H316N62O56S6
QMPW
C
4545.33
8.59
8
3
16
+4
6.94
0.179
81.63
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1865
41.03
12
Residue Composition
number
5
A
4
R
2
N
2
D
6
C
1
E
0
Q
5
G
1
H
1
I
3
L
3
K
0
M
1
F
0
P
2
S
1
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 5 R: 4 N: 2 D: 2 C: 6 E: 1 Q: 0 G: 5 H: 1 I: 1 L: 3 K: 3 M: 0 F: 1 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 5
Chemical Descriptors
43
C189H316N62O56S6
4545.33
8.59
+4
6.94
0.179
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Staphylococcus aureus ATCC 6538

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/
Evidence 2 Activity

Activity

MIC
Antibacterial
3.12 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP

Other

active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albica
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli ATCC 2592

Source & Reference

dbAMP DRAMP

Other

us ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albicans ATCC 36232 (MIC > 100 ug/ml). U
Evidence 4 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Staphylococcus aureus ATCC 6538

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/
Evidence 5 Activity

Activity

MIC
Antifungal
3.12 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albica
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli ATCC 2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

us ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albicans ATCC 36232 (MIC > 100 ug/ml). U
Evidence 7 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Staphylococcus aureus ATCC 6538

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/
Evidence 8 Activity

Activity

MIC
Antiparasitic
3.12 µg/mL

Target

M. luteus ATCC 9341

Source & Reference

DRAMP

Other

active against S. aureus ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albica
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli ATCC 2592

Source & Reference

DRAMP

Other

us ATCC 6538 (MIC 6.25 ug/ml), MRSA (MIC 25 ug/ml), M. luteus ATCC 9341 (MIC 3.12 ug/ml), E.coli ATCC 2592 (MIC>100 ug/ml), P.aeruginosa ATCC 9027 (MIC > 100 ug/ml), and C.albicans ATCC 36232 (MIC > 100 ug/ml). U