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Peptide record

TPDB11995

Antibacterial Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11995
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 42-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GFGCPGNEKKCHNHCKSVKGYKGGYCDGPYIPFVGRPRCKCY
Physicochemical Analysis
C204H306N60O54S6
AQLMTW
G
4655.40
9.11
10
2
9
+6
7.95
-0.831
23.10
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6335
136.08
13
Residue Composition
number
0
A
2
R
2
N
1
D
6
C
1
E
0
Q
8
G
2
H
1
I
0
L
6
K
0
M
2
F
4
P
1
S
0
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 0 R: 2 N: 2 D: 1 C: 6 E: 1 Q: 0 G: 8 H: 2 I: 1 L: 0 K: 6 M: 0 F: 2 P: 4 S: 1 T: 0 W: 0 Y: 4 V: 2
Chemical Descriptors
42
C204H306N60O54S6
4655.40
9.11
+6
7.95
-0.831
Evidence Records 2 records
Evidence 1 Activity

Activity

3% Killing
Toxicity
50 µM
Cytotoxic
3% Killing | 50 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Invasive fungi-derived defensins kill drug-resistant bacterial pathogens. | Peptides | 2018
Evidence 2 Activity

Activity

15% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
15% Hemolysis | 50 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Invasive fungi-derived defensins kill drug-resistant bacterial pathogens. | Peptides | 2018