Back to search

Peptide record

TPDB11990

Antibacterial Anticancer Antifungal Antiparasitic standard
42 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11990
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
QGVRNHVTCRIYGGFCVPIRCPGRTRQIGTCFGRPVKCCRRW
Physicochemical Analysis
C207H335N73O50S6
ADELMS
R
4838.76
11.07
10
0
11
+9
4.70
-0.338
55.48
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
7365
152.21
13
Residue Composition
number
0
A
8
R
1
N
0
D
6
C
0
E
2
Q
6
G
1
H
3
I
0
L
1
K
0
M
2
F
3
P
0
S
3
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 0 R: 8 N: 1 D: 0 C: 6 E: 0 Q: 2 G: 6 H: 1 I: 3 L: 0 K: 1 M: 0 F: 2 P: 3 S: 0 T: 3 W: 1 Y: 1 V: 4
Chemical Descriptors
42
C207H335N73O50S6
4838.76
11.07
+9
4.70
-0.338
Evidence Records 15 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µM

Target

B. subtilis CMCC 63501

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. ente
Evidence 2 Activity

Activity

MIC
Antibacterial
2 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP

Other

ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans
Evidence 3 Activity

Activity

MIC
Antibacterial
1 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC dat
Evidence 4 Activity

Activity

MIC
Antibacterial
4 µM

Target

S. enteritidis

Source & Reference

dbAMP DRAMP

Other

C 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021
Evidence 5 Activity

Activity

MIC
Antibacterial
16 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

(MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
8 µM

Target

B. subtilis CMCC 63501

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. ente
Evidence 7 Activity

Activity

MIC
Antifungal
2 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans
Evidence 8 Activity

Activity

MIC
Antifungal
1 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC dat
Evidence 9 Activity

Activity

MIC
Antifungal
4 µM

Target

S. enteritidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021
Evidence 10 Activity

Activity

MIC
Antifungal
16 µM

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021
Evidence 11 Activity

Activity

MIC
Antiparasitic
8 µM

Target

B. subtilis CMCC 63501

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. ente
Evidence 12 Activity

Activity

MIC
Antiparasitic
2 µM

Target

Enterococcus faecalis ATCC 29212

Source & Reference

DRAMP

Other

ML35 and S. aureus 502A (diffusion, GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans
Evidence 13 Activity

Activity

MIC
Antiparasitic
1 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

GW). Active against B. subtilis CMCC 63501(MIC 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC dat
Evidence 14 Activity

Activity

MIC
Antiparasitic
4 µM

Target

S. enteritidis

Source & Reference

DRAMP

Other

C 8 uM), E. faecalis ATCC 29212 (MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021
Evidence 15 Activity

Activity

MIC
Antiparasitic
16 µM

Target

Candida albicans

Source & Reference

DRAMP

Other

(MIC 2 uM), E. coli (MIC 1 uM), P. aeruginosa ATCC 27853, S. enteritidis (MIC 4 uM), and C. albicans(MIC 16 uM) (MIC data provided by Chunfeng Wang). Updated 9/2017 7/2021