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Peptide record

TPDB11986

Antibacterial Anticancer Antifungal Antiparasitic standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11986
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GKIPVKAIKQAGKVIGKGLRAINIAGTTHDVVSFFRPKKKKH
Physicochemical Analysis
C208H355N63O50
CEMWY
K
4538.50
11.82
13
1
16
+10
11.27
-0.298
92.86
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
4
A
2
R
1
N
1
D
0
C
0
E
1
Q
5
G
2
H
5
I
1
L
9
K
0
M
2
F
2
P
1
S
2
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 4 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 5 H: 2 I: 5 L: 1 K: 9 M: 0 F: 2 P: 2 S: 1 T: 2 W: 0 Y: 0 V: 4
Chemical Descriptors
42
C208H355N63O50
4538.50
11.82
+10
11.27
-0.298
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Escherichia coli 0157H7 ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S
Evidence 2 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

S. typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP

Other

active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP

Other

- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MI
Evidence 4 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

S. typhimurium DT104 ATCC 700408

Source & Reference

dbAMP DRAMP

Other

), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 o
Evidence 5 Activity

Activity

MIC
Antibacterial
6.25 µg/mL

Target

L. monocytogenes ATCC 19115

Source & Reference

dbAMP DRAMP

Other

iae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
6.25-12.5 µg/mL

Target

Staphylococcus aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39

Source & Reference

dbAMP DRAMP

Other

m DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Escherichia coli 0157H7 ATCC 25922

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S
Evidence 8 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

S. typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug
Evidence 9 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP Antifungipept

Other

- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MI
Evidence 10 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

S. typhimurium DT104 ATCC 700408

Source & Reference

dbAMP DRAMP Antifungipept

Other

), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 o
Evidence 11 Activity

Activity

MIC
Antifungal
6.25 µg/mL

Target

L. monocytogenes ATCC 19115

Source & Reference

dbAMP DRAMP Antifungipept

Other

iae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
6.25-12.5 µg/mL

Target

Staphylococcus aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39

Source & Reference

dbAMP DRAMP Antifungipept

Other

m DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Escherichia coli 0157H7 ATCC 25922

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S
Evidence 14 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

S. typhimurium ATCC 14028

Source & Reference

DRAMP

Other

active against Gram- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug
Evidence 15 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

- E. coli 0157H7 ATCC 25922 (MIC 6.25 ug/ml), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MI
Evidence 16 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

S. typhimurium DT104 ATCC 700408

Source & Reference

DRAMP

Other

), S. typhimurium ATCC 14028 (MIC 6.25 ug/ml), K. pneumoniae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 o
Evidence 17 Activity

Activity

MIC
Antiparasitic
6.25 µg/mL

Target

L. monocytogenes ATCC 19115

Source & Reference

DRAMP

Other

iae ATCC 13883 (MIC 6.25 ug/ml), S. typhimurium DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).
Evidence 18 Activity

Activity

MIC
Antiparasitic
6.25-12.5 µg/mL

Target

Staphylococcus aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39

Source & Reference

DRAMP

Other

m DT104 ATCC 700408 (MIC 6.25 ug/ml), Gram+ L. monocytogenes ATCC 19115 (MIC 6.25 ug/ml), S. aureus ATCC 25923 or MRSA 43300 or MRSA BAA-39 (MIC 6.25-12.5 ug/ml).