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Peptide record

TPDB11983

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11983
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 i2APP
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RGFRKHFNKLVKKVKHTISETAHVAKDTAVIAGSGAAVVAAT
Physicochemical Analysis
C197H329N61O54
CQMPWY
A
4416.16
11.16
11
2
19
+6
10.58
-0.002
88.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
7
Residue Composition
number
8
A
2
R
1
N
1
D
0
C
1
E
0
Q
3
G
3
H
2
I
1
L
6
K
0
M
2
F
0
P
2
S
4
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 8 R: 2 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 3 I: 2 L: 1 K: 6 M: 0 F: 2 P: 0 S: 2 T: 4 W: 0 Y: 0 V: 6
Chemical Descriptors
42
C197H329N61O54
4416.16
11.16
+6
10.58
-0.002
Evidence Records 3 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
4% Hemolysis | 10 | µM | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans. | J Biol Chem | 2002
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Bovine erythrocytes

Target

Bovine erythrocytes

Source & Reference

NA
DBAASP
Epithelial innate immunity. A novel antimicrobial peptide with antiparasitic activity in the blood-sucking insect Stomoxys calcitrans. | J Biol Chem | 2002
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.12372834]2% hemolytic activity at 10 µM, 9% hemolytic activity at 100 µM against bovine red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
J. Biol. Chem. 2002 277: 49921-49926.##Biopolymers. 2006 Feb 5 81(2):92-103.