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Peptide record

TPDB11979

Antibacterial Antifungal Antiparasitic Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11979
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP dbAMP 3.0 i2APP
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFRKRFNKLVKKVKHTIKETANVSKDVAIVAGSGVAVGAAMG
Physicochemical Analysis
C195H333N59O53S1
CQPWY
KV
4384.21
11.23
10
2
19
+7
9.99
0.048
90.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
6
A
2
R
2
N
1
D
0
C
1
E
0
Q
5
G
1
H
2
I
1
L
7
K
1
M
2
F
0
P
2
S
2
T
0
W
0
Y
7
V
Amino Acid Distribution
A: 6 R: 2 N: 2 D: 1 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 2 L: 1 K: 7 M: 1 F: 2 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 7
Chemical Descriptors
42
C195H333N59O53S1
4384.21
11.23
+7
9.99
0.048
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.2 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. fal
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

M. luteus

Source & Reference

dbAMP

Other

Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. falciparum parasite ( Tonk et a
Evidence 3 Activity

Activity

MIC
Antifungal
6.2 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. fal
Evidence 4 Activity

Activity

MIC
Antifungal
37.5 µM

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. falciparum parasite ( Tonk et a
Evidence 5 Activity

Activity

MIC
Antiparasitic
6.2 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. fal
Evidence 6 Activity

Activity

MIC
Antiparasitic
37.5 µM

Target

M. luteus

Source & Reference

dbAMP 3.0

Other

Active against E. coli (MIC 6.2 uM) and M. luteus (MIC 37.5 uM). It showed inhibitory activity against the blood-stage P. falciparum parasite ( Tonk et a
Evidence 7 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019
Evidence 8 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019