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Peptide record

TPDB11967

Antibacterial Antifungal Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11967
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
APKVNVNALKKGGHVIKKGLGVIGAAGTAHEVYNHVRNRNQG
Physicochemical Analysis
C191H319N65O53
DCMFSW
G
4374.04
11.11
10
1
16
+6
11.70
-0.433
90.48
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
34.06
8
Residue Composition
number
5
A
2
R
5
N
0
D
0
C
1
E
1
Q
7
G
3
H
2
I
2
L
5
K
0
M
0
F
1
P
0
S
1
T
0
W
1
Y
6
V
Amino Acid Distribution
A: 5 R: 2 N: 5 D: 0 C: 0 E: 1 Q: 1 G: 7 H: 3 I: 2 L: 2 K: 5 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 6
Chemical Descriptors
42
C191H319N65O53
4374.04
11.11
+6
11.70
-0.433
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8.7 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107
Evidence 2 Activity

Activity

MIC
Antibacterial
1107.5 µg/mL

Target

P.aeruginosa

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >110
Evidence 3 Activity

Activity

MIC
Antibacterial
843 µg/mL

Target

S.marcescens

Source & Reference

dbAMP

Other

active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
>1107.5 µg/mL

Target

S.aureus

Source & Reference

dbAMP

Other

oli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
>1107.5 µg/mL

Target

B.cereus

Source & Reference

dbAMP

Other

(MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
8.7 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107
Evidence 7 Activity

Activity

MIC
Antifungal
1107.5 µg/mL

Target

P.aeruginosa

Source & Reference

dbAMP CAFPdb

Other

active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >110
Evidence 8 Activity

Activity

MIC
Antifungal
843 µg/mL

Target

S.marcescens

Source & Reference

dbAMP CAFPdb

Other

active against Gram- E. coli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
>1107.5 µg/mL

Target

S.aureus

Source & Reference

dbAMP CAFPdb

Other

oli (MIC 8.7 ug/ml), P.aeruginosa (MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
>1107.5 µg/mL

Target

B.cereus

Source & Reference

dbAMP CAFPdb

Other

(MIC 1107.5 ug/ml), S.marcescens (MIC 843 ug/ml), Gram+ S.aureus (MIC >1107.5 ug/ml), and B.cereus (MIC >1107.5 ug/ml).
Evidence 11 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular Identification of a Moricin Family Antimicrobial Peptide (Px-Mor) From Plutella xylostella With Activities Against the Opportunistic Human Pathogen Aureobasidium pullulans. | Front Microbiol | 2019