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Peptide record

TPDB11965

Antibacterial Anticancer Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11965
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
DLIWKLLVKAQEKFGRGKPSKRVKKMRRQWQACKSSHHHHHH
Physicochemical Analysis
C229H367N79O53S2
NTY
K
5139.05
11.62
18
2
12
+10
15.28
-1.367
55.71
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
11000
214.05
7
Residue Composition
number
2
A
4
R
0
N
1
D
1
C
1
E
3
Q
2
G
6
H
1
I
3
L
8
K
1
M
1
F
1
P
3
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 1 C: 1 E: 1 Q: 3 G: 2 H: 6 I: 1 L: 3 K: 8 M: 1 F: 1 P: 1 S: 3 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
42
C229H367N79O53S2
5139.05
11.62
+10
15.28
-1.367
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Heterologous expression of a broad-spectrum chimeric antimicrobial peptide in Lactococcus lactis: Its safety and molecular modeling evaluation | Microb Pathog | 2018
Evidence 2 Activity

Activity

2.5% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
2.5% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Heterologous expression of a broad-spectrum chimeric antimicrobial peptide in Lactococcus lactis: Its safety and molecular modeling evaluation | Microb Pathog | 2018
Evidence 3 Activity

Activity

4% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 250 | µg/mL | target cell: Chicken erythrocytes

Target

Chicken erythrocytes

Source & Reference

NA
DBAASP
Recombinant production of a chimeric antimicrobial peptide in E. coli and assessment of its activity against some avian clinically isolated pathogens. | Microb Pathog | 2018