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Peptide record

TPDB11962

Antibacterial Antifungal Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB11962
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SPAIWGCDSFLGYCRLACFAHEASVGQKECAEGMLCCIPNVF
Physicochemical Analysis
C198H297N51O57S7
T
C
4528.26
4.62
3
4
18
-2
1.52
0.502
72.14
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7365
162.65
12
Residue Composition
number
5
A
1
R
1
N
1
D
6
C
3
E
1
Q
4
G
1
H
2
I
3
L
1
K
1
M
3
F
2
P
3
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 1 C: 6 E: 3 Q: 1 G: 4 H: 1 I: 2 L: 3 K: 1 M: 1 F: 3 P: 2 S: 3 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
42
C198H297N51O57S7
4528.26
4.62
-2
1.52
0.502
Evidence Records 3 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel defensin-like antimicrobial peptide from the skin secretions of the tree frog, Theloderma kwangsiensis. | Gene | 2015
Evidence 2 Activity

Activity

3% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel defensin-like antimicrobial peptide from the skin secretions of the tree frog, Theloderma kwangsiensis. | Gene | 2015
Evidence 3 Activity

Activity

6% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
6% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel defensin-like antimicrobial peptide from the skin secretions of the tree frog, Theloderma kwangsiensis. | Gene | 2015