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Peptide record

TPDB11946

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB11946
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 41-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
SPRVSRRYGRPFGGRPFVGGQFGGRPGCVCIRSPCPCANYG
Physicochemical Analysis
C189H292N64O49S4
DEHLKMTW
G
4373.04
11.00
7
0
10
+7
3.35
-0.473
33.17
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
3230
73.86
11
Residue Composition
number
1
A
7
R
1
N
0
D
4
C
0
E
1
Q
9
G
0
H
1
I
0
L
0
K
0
M
3
F
6
P
3
S
0
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 4 E: 0 Q: 1 G: 9 H: 0 I: 1 L: 0 K: 0 M: 0 F: 3 P: 6 S: 3 T: 0 W: 0 Y: 2 V: 3
Chemical Descriptors
41
C189H292N64O49S4
4373.04
11.00
+7
3.35
-0.473
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive A. viridans, M. Luteus, (MIC 0.2-0.78 ug/ml) and Gram-negative V. harveyi and V. anguillarum. Bactericidal effects were verified. Provided by Biswajit Mishra.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive A. viridans, M. Luteus, (MIC 0.2-0.78 ug/ml) and Gram-negative V. harveyi and V. anguillarum. Bactericidal effects were verified. Provided by Biswajit Mishra.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against Gram-positive A. viridans, M. Luteus, (MIC 0.2-0.78 ug/ml) and Gram-negative V. harveyi and V. anguillarum. Bactericidal effects were verified. Provided by Biswajit Mishra.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against Gram-positive A. viridans, M. Luteus, (MIC 0.2-0.78 ug/ml) and Gram-negative V. harveyi and V. anguillarum. Bactericidal effects were verified. Provided by Biswajit Mishra.
Evidence 5 Activity

Activity

5.7% Hemolysis
Toxicity
40.5 µM
Hemolytic Cytotoxic
5.7% Hemolysis | 40.5 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Production of antimicrobial peptide arasin-like Sp in Escherichia coli via an ELP-intein self-cleavage system. | Biotechnol J | 2022