Back to search

Peptide record

TPDB11944

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
41 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11944
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 41-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
APGNKAECEREKGYCGFLKCSFPFVVSGKCSRFFFCCKNIW
Physicochemical Analysis
C212H313N55O54S6
DQHMT
CF
4688.51
8.58
7
3
14
+4
2.72
-0.080
38.05
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
7365
157.09
12
Residue Composition
number
2
A
2
R
2
N
0
D
6
C
3
E
0
Q
4
G
0
H
1
I
1
L
5
K
0
M
6
F
2
P
3
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 0 C: 6 E: 3 Q: 0 G: 4 H: 0 I: 1 L: 1 K: 5 M: 0 F: 6 P: 2 S: 3 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
41
C212H313N55O54S6
4688.51
8.58
+4
2.72
-0.080
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.25 µg/mL

Target

Staphylococcus aureus 1056 MRSA

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
6.2 µg/mL

Target

Candida albicans 3153A

Source & Reference

dbAMP DRAMP

Other

ctive against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).
Evidence 3 Activity

Activity

MIC
Antifungal
1.25 µg/mL

Target

Staphylococcus aureus 1056 MRSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
6.2 µg/mL

Target

Candida albicans 3153A

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ctive against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).
Evidence 5 Activity

Activity

MIC
Antiparasitic
1.25 µg/mL

Target

Staphylococcus aureus 1056 MRSA

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).
Evidence 6 Activity

Activity

MIC
Antiparasitic
6.2 µg/mL

Target

Candida albicans 3153A

Source & Reference

DRAMP

Other

ctive against S. aureus 1056 MRSA (MIC 1.25 ug/ml), E. coli O157:H7 (MIC 0.96 ug/ml), and C. albicans 3153A (MIC 6.2 ug/ml).