Back to search

Peptide record

TPDB11939

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
41 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11939
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 41-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
DTLACRQSHGSCSFVACRAPSVDIGTCRGGKLKCCKWAPSS
Physicochemical Analysis
C177H289N57O55S6
NEMY
CS
4287.95
8.60
7
2
11
+4
5.01
-0.129
52.44
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5875
137.01
15
Residue Composition
number
4
A
3
R
0
N
2
D
6
C
0
E
1
Q
4
G
1
H
1
I
2
L
3
K
0
M
1
F
2
P
6
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 3 N: 0 D: 2 C: 6 E: 0 Q: 1 G: 4 H: 1 I: 1 L: 2 K: 3 M: 0 F: 1 P: 2 S: 6 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
41
C177H289N57O55S6
4287.95
8.60
+4
5.01
-0.129
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

C. jejuni

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (M
Evidence 2 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.enterica serovar Typhimurium

Source & Reference

dbAMP

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml)
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug
Evidence 4 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

P.aeruginosa

Source & Reference

dbAMP

Other

(MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/m
Evidence 5 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Clostridium perfringens

Source & Reference

dbAMP

Other

Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fung
Evidence 6 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP

Other

E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml)
Evidence 7 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since
Evidence 8 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP

Other

aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since it has a different sequence, it
Evidence 9 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

C. jejuni

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (M
Evidence 10 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

S.enterica serovar Typhimurium

Source & Reference

dbAMP CAFPdb Antifungipept

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml)
Evidence 11 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug
Evidence 12 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

P.aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/m
Evidence 13 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Clostridium perfringens

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fung
Evidence 14 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Streptococcus pyogenes

Source & Reference

dbAMP CAFPdb Antifungipept

Other

E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml)
Evidence 15 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since
Evidence 16 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. cerevisiae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since it has a different sequence, it
Evidence 17 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

C. jejuni

Source & Reference

NA

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (M
Evidence 18 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

S.enterica serovar Typhimurium

Source & Reference

NA

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml)
Evidence 19 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug
Evidence 20 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

P.aeruginosa

Source & Reference

NA

Other

(MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/m
Evidence 21 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Clostridium perfringens

Source & Reference

NA

Other

Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fung
Evidence 22 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Streptococcus pyogenes

Source & Reference

NA

Other

E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml)
Evidence 23 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since
Evidence 24 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

S. cerevisiae

Source & Reference

NA

Other

aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since it has a different sequence, it
Evidence 25 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

C. jejuni

Source & Reference

NA

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (M
Evidence 26 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

S.enterica serovar Typhimurium

Source & Reference

NA

Other

The synthetic peptide is tested against Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml)
Evidence 27 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

Gram- bacteria C. jejuni (MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug
Evidence 28 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

P.aeruginosa

Source & Reference

NA

Other

(MIC 64 ug/ml), S.enterica serovar Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/m
Evidence 29 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

Clostridium perfringens

Source & Reference

NA

Other

Typhimurium (MIC >128 ug/ml), E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fung
Evidence 30 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

Streptococcus pyogenes

Source & Reference

NA

Other

E. coli (MIC 64 ug/ml), P.aeruginosa (MIC>128 ug/ml), Gram+ C. perfringens (MIC 8 ug/ml), S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml)
Evidence 31 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

S. pyogenes (MIC 64 ug/ml), S.aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since
Evidence 32 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

S. cerevisiae

Source & Reference

NA

Other

aureus (MIC > 128 ug/ml), B.cereus (MIC > 128 ug/ml), fungi C. albicans (MIC 8 ug/ml) and S. cerevisiae (MIC 8 ug/ml). The recombinant form is similarly or less active. Since it has a different sequence, it