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Peptide record

TPDB11929

Antibacterial Toxicity standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB11929
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 41-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GWLDVAKKIGKAAFNVAKNFLFNKAVNFAAKGIKKAVDLWG
Physicochemical Analysis
C212H331N55O50
RCEQHMPSTY
AK
4450.30
10.74
8
2
23
+6
0.50
0.176
95.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
247.17
4
Residue Composition
number
8
A
0
R
4
N
2
D
0
C
0
E
0
Q
4
G
0
H
2
I
3
L
8
K
0
M
4
F
0
P
0
S
0
T
2
W
0
Y
4
V
Amino Acid Distribution
A: 8 R: 0 N: 4 D: 2 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 2 L: 3 K: 8 M: 0 F: 4 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 4
Chemical Descriptors
41
C212H331N55O50
4450.30
10.74
+6
0.50
0.176
Evidence Records 1 records
Evidence 1 Activity

Activity

HC50
Toxicity
0.6
Hemolytic
Hemolytic_activity: [Ref.22391524]HC50=0.6±0.1 µmol/L against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2012 Jun 56(6):3004-10.