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Peptide record

TPDB11916

Antibacterial Antifungal standard
40 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11916
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 40-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
AYVLDEPKPIKDLEKSLQHNLVYCRRLVLEYFLKSIFEYH
Physicochemical Analysis
C230H354N56O61S1
GMTW
L
4911.74
7.30
8
6
19
+0
9.44
-0.273
112.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5960
121.34
9
Residue Composition
number
1
A
2
R
1
N
2
D
1
C
4
E
1
Q
0
G
2
H
2
I
7
L
4
K
0
M
2
F
2
P
2
S
0
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 2 C: 1 E: 4 Q: 1 G: 0 H: 2 I: 2 L: 7 K: 4 M: 0 F: 2 P: 2 S: 2 T: 0 W: 0 Y: 4 V: 3
Chemical Descriptors
40
C230H354N56O61S1
4911.74
7.30
+0
9.44
-0.273
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

NA

Other

Active against E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. al
Evidence 2 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

NA

Other

Active against E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These
Evidence 3 Activity

Activity

MIC
Antibacterial
24 µg/mL

Target

p. ATCC55121

Source & Reference

NA

Other

inst E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These are MIC50. Reg. 9/2014 SEQ updated 8/2017.
Evidence 4 Activity

Activity

MIC
Antibacterial
6 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

NA

Other

g/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These are MIC50. Reg. 9/2014 SEQ updated 8/2017. GW.
Evidence 5 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Escherichia coli ATCC25922

Source & Reference

CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. al
Evidence 6 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Staphylococcus aureus ATCC25923

Source & Reference

CAFPdb Antifungipept

Other

Active against E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These
Evidence 7 Activity

Activity

MIC
Antifungal
24 µg/mL

Target

p. ATCC55121

Source & Reference

CAFPdb Antifungipept

Other

inst E. coli ATCC25922 (MIC 12 ug/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These are MIC50. Reg. 9/2014 SEQ updated 8/2017.
Evidence 8 Activity

Activity

MIC
Antifungal
6 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

CAFPdb Antifungipept

Other

g/ml), S. aureus ATCC25923 (MIC 12 ug/ml), Streptococcus sp. ATCC55121 (MIC 24 ug/ml) and C. albicans ATCC2002 (MIC 6 ug/ml). These are MIC50. Reg. 9/2014 SEQ updated 8/2017. GW.