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Peptide record

TPDB11905

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB11905
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AVPpred-BWR
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
YDLSKNCRLRGGICYIGKCPRRFFRSGSCSRGNVCCLRFG
Physicochemical Analysis
C193H311N65O51S6
AEQHMTW
R
4550.36
10.01
9
1
11
+8
1.81
-0.290
56.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
3355
73.73
14
Residue Composition
number
0
A
7
R
2
N
1
D
6
C
0
E
0
Q
6
G
0
H
2
I
3
L
2
K
0
M
3
F
1
P
4
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 7 N: 2 D: 1 C: 6 E: 0 Q: 0 G: 6 H: 0 I: 2 L: 3 K: 2 M: 0 F: 3 P: 1 S: 4 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
40
C193H311N65O51S6
4550.36
10.01
+8
1.81
-0.290
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, purification and de novo sequencing of TBD-1, the first beta-defensin from leukocytes of reptiles. | Proteomics | 2009
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.19253295] It has no hemolytic activity against human erythrocytes up to 25 mmol/L

Target

erythrocytes

Source & Reference

NA
DRAMP
Proteomics. 2009 Mar 9(5):1364-1373.