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Peptide record

TPDB11902

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11902
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GFGCNGPWDEDDMQCHNHCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
C189H273N53O56S7
RLT
G
4407.99
7.64
7
4
10
+1
5.65
-0.695
19.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
10345
234.69
13
Residue Composition
number
1
A
0
R
2
N
3
D
6
C
1
E
1
Q
8
G
2
H
1
I
0
L
5
K
1
M
2
F
1
P
1
S
0
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 3 C: 6 E: 1 Q: 1 G: 8 H: 2 I: 1 L: 0 K: 5 M: 1 F: 2 P: 1 S: 1 T: 0 W: 1 Y: 3 V: 1
Chemical Descriptors
40
C189H273N53O56S7
4407.99
7.64
+1
5.65
-0.695
Evidence Records 61 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.25-8 µg/mL

Target

S. pneumoniae PSSP

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.06
Evidence 2 Activity

Activity

MIC
Antibacterial
0.125-4 µg/mL

Target

S. pneumoniae PRSP

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug
Evidence 3 Activity

Activity

MIC
Antibacterial
0.063-0.5 µg/mL

Target

Streptococcus pyogenes ESSP

Source & Reference

dbAMP DRAMP

Other

e PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) an
Evidence 4 Activity

Activity

MIC
Antibacterial
4-32 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP DRAMP

Other

e PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. ep
Evidence 5 Activity

Activity

MIC
Antibacterial
16-32 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP DRAMP

Other

yogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermi
Evidence 6 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.aureus

Source & Reference

dbAMP DRAMP

Other

MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis
Evidence 7 Activity

Activity

MIC
Antibacterial
8-32 µg/mL

Target

Staphylococcus epidermidis MSSE

Source & Reference

dbAMP DRAMP

Other

g/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4
Evidence 8 Activity

Activity

MIC
Antibacterial
4-16 µg/mL

Target

Staphylococcus epidermidis MRSE

Source & Reference

dbAMP DRAMP

Other

6-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5
Evidence 9 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

>128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16
Evidence 10 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MI
Evidence 11 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

E.faecium

Source & Reference

dbAMP DRAMP

Other

MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thur
Evidence 12 Activity

Activity

MIC
Antibacterial
2-8 µg/mL

Target

C. diphtheriae

Source & Reference

dbAMP DRAMP

Other

strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Mis
Evidence 13 Activity

Activity

MIC
Antibacterial
1-2 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP DRAMP

Other

ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 14 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

B. thuringiensis

Source & Reference

dbAMP DRAMP

Other

ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 15 Activity

Activity

MIC
Antifungal
0.25-8 µg/mL

Target

S. pneumoniae PSSP

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.06
Evidence 16 Activity

Activity

MIC
Antifungal
0.125-4 µg/mL

Target

S. pneumoniae PRSP

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug
Evidence 17 Activity

Activity

MIC
Antifungal
0.063-0.5 µg/mL

Target

Streptococcus pyogenes ESSP

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

e PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) an
Evidence 18 Activity

Activity

MIC
Antifungal
4-32 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

e PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. ep
Evidence 19 Activity

Activity

MIC
Antifungal
16-32 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

yogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermi
Evidence 20 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

S.aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis
Evidence 21 Activity

Activity

MIC
Antifungal
8-32 µg/mL

Target

Staphylococcus epidermidis MSSE

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4
Evidence 22 Activity

Activity

MIC
Antifungal
4-16 µg/mL

Target

Staphylococcus epidermidis MRSE

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

6-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5
Evidence 23 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

>128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16
Evidence 24 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MI
Evidence 25 Activity

Activity

MIC
Antifungal
>128 µg/mL

Target

E.faecium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thur
Evidence 26 Activity

Activity

MIC
Antifungal
2-8 µg/mL

Target

C. diphtheriae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Mis
Evidence 27 Activity

Activity

MIC
Antifungal
1-2 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 28 Activity

Activity

MIC
Antifungal
32-64 µg/mL

Target

B. thuringiensis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 29 Activity

Activity

MIC
Antiparasitic
0.25-8 µg/mL

Target

S. pneumoniae PSSP

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.06
Evidence 30 Activity

Activity

MIC
Antiparasitic
0.125-4 µg/mL

Target

S. pneumoniae PRSP

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug
Evidence 31 Activity

Activity

MIC
Antiparasitic
0.063-0.5 µg/mL

Target

Streptococcus pyogenes ESSP

Source & Reference

dbAMP 3.0 DRAMP

Other

e PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) an
Evidence 32 Activity

Activity

MIC
Antiparasitic
4-32 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP 3.0 DRAMP

Other

e PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. ep
Evidence 33 Activity

Activity

MIC
Antiparasitic
16-32 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP 3.0 DRAMP

Other

yogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermi
Evidence 34 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

S.aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis
Evidence 35 Activity

Activity

MIC
Antiparasitic
8-32 µg/mL

Target

Staphylococcus epidermidis MSSE

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4
Evidence 36 Activity

Activity

MIC
Antiparasitic
4-16 µg/mL

Target

Staphylococcus epidermidis MRSE

Source & Reference

dbAMP 3.0 DRAMP

Other

6-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5
Evidence 37 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

>128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16
Evidence 38 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MI
Evidence 39 Activity

Activity

MIC
Antiparasitic
>128 µg/mL

Target

E.faecium

Source & Reference

dbAMP 3.0 DRAMP

Other

MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thur
Evidence 40 Activity

Activity

MIC
Antiparasitic
2-8 µg/mL

Target

C. diphtheriae

Source & Reference

dbAMP 3.0 DRAMP

Other

strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Mis
Evidence 41 Activity

Activity

MIC
Antiparasitic
1-2 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP 3.0 DRAMP

Other

ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 42 Activity

Activity

MIC
Antiparasitic
32-64 µg/mL

Target

B. thuringiensis

Source & Reference

dbAMP 3.0 DRAMP

Other

ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 43 Activity

Activity

MIC
Antiviral
0.25-8 µg/mL

Target

S. pneumoniae PSSP

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.06
Evidence 44 Activity

Activity

MIC
Antiviral
0.125-4 µg/mL

Target

S. pneumoniae PRSP

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against Gram+ bacteria S. pneumoniae PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug
Evidence 45 Activity

Activity

MIC
Antiviral
0.063-0.5 µg/mL

Target

Streptococcus pyogenes ESSP

Source & Reference

dbAMP 3.0 DRAMP

Other

e PSSP 109 strains (MIC 0.25-8 ug/ml), S. pneumoniae PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) an
Evidence 46 Activity

Activity

MIC
Antiviral
4-32 µg/mL

Target

Staphylococcus aureus MSSA

Source & Reference

dbAMP 3.0 DRAMP

Other

e PRSP 24 strains (MIC 0.125-4 ug/ml), S. pyogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. ep
Evidence 47 Activity

Activity

MIC
Antiviral
16-32 µg/mL

Target

Staphylococcus aureus MRSA

Source & Reference

dbAMP 3.0 DRAMP

Other

yogenes ESSP 12 strains (MIC 0.063-0.5 ug/ml), S. aureus MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermi
Evidence 48 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

S.aureus

Source & Reference

dbAMP 3.0 DRAMP

Other

MSSA 5 strains (MIC 4-32 ug/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis
Evidence 49 Activity

Activity

MIC
Antiviral
8-32 µg/mL

Target

Staphylococcus epidermidis MSSE

Source & Reference

dbAMP 3.0 DRAMP

Other

g/ml), S. aureus MRSA 4 strains (MIC 16-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4
Evidence 50 Activity

Activity

MIC
Antiviral
4-16 µg/mL

Target

Staphylococcus epidermidis MRSE

Source & Reference

dbAMP 3.0 DRAMP

Other

6-32 ug/ml) and 1 strain S.aureus (MIC >128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5
Evidence 51 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

>128 ug/ml), S. epidermidis MSSE (MIC 8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16
Evidence 52 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

Enterococcus faecalis

Source & Reference

dbAMP 3.0 DRAMP

Other

8-32 ug/ml), S. epidermidis MRSE (MIC 4-16 ug/ml), E. faecalis 2 strains (MIC 64 ug/ml), E.faecalis 4 strains (MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MI
Evidence 53 Activity

Activity

MIC
Antiviral
>128 µg/mL

Target

E.faecium

Source & Reference

dbAMP 3.0 DRAMP

Other

MIC128 ug/ml), E. faecium 5 strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thur
Evidence 54 Activity

Activity

MIC
Antiviral
2-8 µg/mL

Target

C. diphtheriae

Source & Reference

dbAMP 3.0 DRAMP

Other

strains VSEF or 3 strains VREF (MIC 16-64 ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Mis
Evidence 55 Activity

Activity

MIC
Antiviral
1-2 µg/mL

Target

Corynebacterium jeikeium

Source & Reference

dbAMP 3.0 DRAMP

Other

ug/ml, or 2 strains E.faecium (MIC >128 ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 56 Activity

Activity

MIC
Antiviral
32-64 µg/mL

Target

B. thuringiensis

Source & Reference

dbAMP 3.0 DRAMP

Other

ug/ml), C. diphtheriae 4 strains (MIC 2-8 ug/ml), C. jeikeium 3 strains (MIC 1-2 ug/ml), B. thuringiensis 3 strains (MIC 32-64 ug/ml). Misc. strains, see the ref.
Evidence 57 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human bronchial epithelial cells

Target

Human bronchial epithelial cells

Source & Reference

NA
DBAASP
Plectasin has antibacterial activity and no affect on cell viability or IL-8 production. | Biochem Biophys Res Commun | 2008
Evidence 58 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human Lung Fibroblasts

Target

Human Lung Fibroblasts

Source & Reference

NA
DBAASP
Plectasin has antibacterial activity and no affect on cell viability or IL-8 production. | Biochem Biophys Res Commun | 2008
Evidence 59 Activity

Activity

5% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 125 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Expression of plectasin in Pichia pastoris and its characterization as a new antimicrobial peptide against Staphyloccocus and Streptococcus. | Protein Expr Purif | 2011
Evidence 60 Activity

Activity

5.19% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
5.19% Hemolysis | 125 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
A recombinant fungal defensin-like peptide-P2 combats multidrug-resistant Staphylococcus aureus and biofilms. | Appl Microbiol Biotechnol | 2019
Evidence 61 Activity

Activity

1% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
1% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010