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Peptide record

TPDB11896

Antibacterial Antifungal standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB11896
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 40-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GWLRDFGKRIERVGQHTRDATIQAIGVAQQAANVAATVRG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C186H306N64O55
CMPSY
A
4318.87
11.83
7
3
17
+3
2.18
-0.327
85.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
1.27
8
Residue Composition
number
7
A
5
R
1
N
2
D
0
C
1
E
4
Q
5
G
1
H
3
I
1
L
1
K
0
M
1
F
0
P
0
S
3
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 7 R: 5 N: 1 D: 2 C: 0 E: 1 Q: 4 G: 5 H: 1 I: 3 L: 1 K: 1 M: 0 F: 1 P: 0 S: 0 T: 3 W: 1 Y: 0 V: 4
Chemical Descriptors
40 reviewed residue count
C186H306N64O55 sequence-only estimate (linear, free termini)
4318.87 sequence-only estimate (linear, free termini)
11.83 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
2.18 sequence-only estimate (linear, free termini)
-0.327 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.0 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 5.0 uM) (name corrected A.P.D. 10/2022).
Evidence 2 Activity

Activity

MIC
Antifungal
5.0 µM

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 5.0 uM) (name corrected A.P.D. 10/2022).