Back to search

Peptide record

TPDB11874

Antibacterial Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11874
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 40-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
Physicochemical Analysis
C194H339N69O52S6
NDHMFW
R
4662.62
10.43
13
2
9
+11
12.36
-0.897
56.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3355
71.96
13
Residue Composition
number
1
A
7
R
0
N
0
D
6
C
2
E
2
Q
4
G
0
H
1
I
3
L
6
K
0
M
0
F
1
P
2
S
1
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 6 E: 2 Q: 2 G: 4 H: 0 I: 1 L: 3 K: 6 M: 0 F: 0 P: 1 S: 2 T: 1 W: 0 Y: 2 V: 2
Chemical Descriptors
40
C194H339N69O52S6
4662.62
10.43
+11
12.36
-0.897
Evidence Records 3 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins. | Biopolymers | 2005
Evidence 2 Activity

Activity

2% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins. | Biopolymers | 2005
Evidence 3 Activity

Activity

12% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Engineering disulfide bonds of the novel human beta-defensins hBD-27 and hBD-28: differences in disulfide formation and biological activity among human beta-defensins. | Biopolymers | 2005