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Peptide record

TPDB11868

Antibacterial Anticancer Antifungal Antiparasitic standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB11868
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
KRFHSVGSLIQRHQQMIRDKSEATRHGIRIITRPKLLLAS
Physicochemical Analysis
C204H350N70O54S1
NCWY
R
4679.52
12.41
12
2
14
+7
11.55
-0.565
100.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
9
Residue Composition
number
2
A
6
R
0
N
1
D
0
C
1
E
3
Q
2
G
3
H
5
I
4
L
3
K
1
M
1
F
1
P
4
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 1 C: 0 E: 1 Q: 3 G: 2 H: 3 I: 5 L: 4 K: 3 M: 1 F: 1 P: 1 S: 4 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
40
C204H350N70O54S1
4679.52
12.41
+7
11.55
-0.565
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9-18 µg/mL

Target

C. neoformans

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
it killed these bacteria under low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

R. rubra

Source & Reference

dbAMP

Other

low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114
Evidence 3 Activity

Activity

MIC
Antibacterial
>114 µg/mL

Target

C.albicans

Source & Reference

dbAMP

Other

e against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 u
Evidence 4 Activity

Activity

MIC
Antibacterial
>114 µg/mL

Target

C.parapsilosis

Source & Reference

dbAMP

Other

neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not
Evidence 5 Activity

Activity

MIC
Antibacterial
>114 µg/mL

Target

C.tropicalis

Source & Reference

dbAMP

Other

rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major
Evidence 6 Activity

Activity

MIC
Antibacterial
>114 µg/mL

Target

P.etchellsii

Source & Reference

dbAMP

Other

lbicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major function of eCATH3 is not antimicr
Evidence 7 Activity

Activity

MIC
Antifungal
9-18 µg/mL

Target

C. neoformans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
it killed these bacteria under low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/
Evidence 8 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

R. rubra

Source & Reference

dbAMP CAFPdb Antifungipept

Other

low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114
Evidence 9 Activity

Activity

MIC
Antifungal
>114 µg/mL

Target

C.albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

e against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 u
Evidence 10 Activity

Activity

MIC
Antifungal
>114 µg/mL

Target

C.parapsilosis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not
Evidence 11 Activity

Activity

MIC
Antifungal
>114 µg/mL

Target

C.tropicalis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major
Evidence 12 Activity

Activity

MIC
Antifungal
>114 µg/mL

Target

P.etchellsii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

lbicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major function of eCATH3 is not antimicr
Evidence 13 Activity

Activity

MIC
Antiparasitic
9-18 µg/mL

Target

C. neoformans

Source & Reference

NA

Other

it killed these bacteria under low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/
Evidence 14 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

R. rubra

Source & Reference

NA

Other

low ionic conditions. Fungi: Active against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114
Evidence 15 Activity

Activity

MIC
Antiparasitic
>114 µg/mL

Target

C.albicans

Source & Reference

NA

Other

e against fungi various C. neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 u
Evidence 16 Activity

Activity

MIC
Antiparasitic
>114 µg/mL

Target

C.parapsilosis

Source & Reference

NA

Other

neoformans (MIC 9-18 ug/ml), R. rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not
Evidence 17 Activity

Activity

MIC
Antiparasitic
>114 µg/mL

Target

C.tropicalis

Source & Reference

NA

Other

rubra (MIC 37.5 ug/ml) but not C.albicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major
Evidence 18 Activity

Activity

MIC
Antiparasitic
>114 µg/mL

Target

P.etchellsii

Source & Reference

NA

Other

lbicans (MIC>114 ug/ml),C.parapsilosis (MIC>114 ug/ml), C.tropicalis (MIC>114 ug/ml), and P.etchellsii (MIC>114 ug/ml) in Sabouraud medium (not active in RPMI). If the major function of eCATH3 is not antimicr