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Peptide record

TPDB11849

Antibacterial Anticancer Antifungal Antiparasitic standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11849
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
C217H354N62O55
CHMWY
K
4711.58
11.10
11
5
15
+6
11.53
-0.569
87.44
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
1
A
5
R
1
N
2
D
0
C
3
E
1
Q
2
G
0
H
3
I
4
L
6
K
0
M
5
F
1
P
2
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 1 D: 2 C: 0 E: 3 Q: 1 G: 2 H: 0 I: 3 L: 4 K: 6 M: 0 F: 5 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
39
C217H354N62O55
4711.58
11.10
+6
11.53
-0.569
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
ctive against E. coli and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faec
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epi
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µM

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

ve against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epidermidis (MIC> 100 uM). Lac
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
ctive against E. coli and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faec
Evidence 5 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP DRAMP

Other

and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epi
Evidence 6 Activity

Activity

MIC
Antifungal
50 µM

Target

Klebsiella pneumoniae

Source & Reference

dbAMP DRAMP

Other

ve against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epidermidis (MIC> 100 uM). Lac
Evidence 7 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
ctive against E. coli and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faec
Evidence 8 Activity

Activity

MIC
Antiparasitic
12.5 µM

Target

Pseudomonas aeruginosa

Source & Reference

DRAMP

Other

and B. megaterium. Also active against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epi
Evidence 9 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Klebsiella pneumoniae

Source & Reference

DRAMP

Other

ve against uropathogenic microorganisms E. coli (MIC 25 uM), P. aeruginosa (MIC 12.5 uM), K. pneumoniae (MIC 50 uM), P.mirablis (MIC> 100 uM), E.faecalis (MIC> 100 uM), and S.epidermidis (MIC> 100 uM). Lac