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Peptide record

TPDB11844

Antibacterial Anticancer Antifungal Antiparasitic standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11844
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GWLKKIGKKIERVGQHTRDATIQGLGIAQQAANVAATAR
Physicochemical Analysis
C181H308N60O52
CMFPSY
A
4156.81
11.53
8
2
16
+5
8.55
-0.390
92.82
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
132.31
8
Residue Composition
number
7
A
3
R
1
N
1
D
0
C
1
E
4
Q
5
G
1
H
4
I
2
L
4
K
0
M
0
F
0
P
0
S
3
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 4 G: 5 H: 1 I: 4 L: 2 K: 4 M: 0 F: 0 P: 0 S: 0 T: 3 W: 1 Y: 0 V: 2
Chemical Descriptors
39
C181H308N60O52
4156.81
11.53
+5
8.55
-0.390
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

Escherichia coli K12 or NIHJ

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinan
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µg/mL

Target

S. sonnei JS11746

Source & Reference

dbAMP DRAMP

Other

active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C60
Evidence 3 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

P. uulgaris OX19

Source & Reference

dbAMP DRAMP

Other

tive against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 4
Evidence 4 Activity

Activity

MIC
Antibacterial
0.2 µg/mL

Target

Escherichia coli C600

Source & Reference

dbAMP DRAMP

Other

12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
1.0 µg/mL

Target

B. megaterium BKM 41

Source & Reference

dbAMP DRAMP

Other

X19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

dbAMP DRAMP

Other

is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

Escherichia coli K12 or NIHJ

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinan
Evidence 8 Activity

Activity

MIC
Antifungal
12.5 µg/mL

Target

S. sonnei JS11746

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C60
Evidence 9 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

P. uulgaris OX19

Source & Reference

dbAMP DRAMP Antifungipept

Other

tive against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 4
Evidence 10 Activity

Activity

MIC
Antifungal
0.2 µg/mL

Target

Escherichia coli C600

Source & Reference

dbAMP DRAMP Antifungipept

Other

12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 11 Activity

Activity

MIC
Antifungal
1.0 µg/mL

Target

B. megaterium BKM 41

Source & Reference

dbAMP DRAMP Antifungipept

Other

X19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

dbAMP DRAMP Antifungipept

Other

is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 13 Activity

Activity

MIC
Antiparasitic
6.3 µg/mL

Target

Escherichia coli K12 or NIHJ

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinan
Evidence 14 Activity

Activity

MIC
Antiparasitic
12.5 µg/mL

Target

S. sonnei JS11746

Source & Reference

DRAMP

Other

active against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C60
Evidence 15 Activity

Activity

MIC
Antiparasitic
6.3 µg/mL

Target

P. uulgaris OX19

Source & Reference

DRAMP

Other

tive against E. coli K12 or NIHJ (MIC 6.3 ug/ml), S. sonnei JS11746 (MIC 12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 4
Evidence 16 Activity

Activity

MIC
Antiparasitic
0.2 µg/mL

Target

Escherichia coli C600

Source & Reference

DRAMP

Other

12.5 ug/ml), and P. uulgaris OX19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 17 Activity

Activity

MIC
Antiparasitic
1.0 µg/mL

Target

B. megaterium BKM 41

Source & Reference

DRAMP

Other

X19 (MIC 6.3 ug/ml). The recombinant form is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).
Evidence 18 Activity

Activity

MIC
Antiparasitic
0.5 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

DRAMP

Other

is active against E. coli C600 (MIC 0.2 ug/ml), B. megaterium BKM 41 (MIC 1.0 ug/ml), and P. aeruginosa PAO1 (MIC 0.5 ug/ml).