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Peptide record

TPDB11841

Antibacterial Anticancer Antifungal Antiparasitic standard
39 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB11841
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia Antifungipept CAFPdb i2APP
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
Physicochemical Analysis
C196H321N59O49S6
NEQHMWV
C
4480.43
10.21
10
1
12
+9
1.57
-0.054
62.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
41.63
13
Residue Composition
number
1
A
5
R
0
N
1
D
6
C
0
E
0
Q
3
G
0
H
2
I
4
L
5
K
0
M
4
F
1
P
5
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 1 C: 6 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 4 K: 5 M: 0 F: 4 P: 1 S: 5 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
39
C196H321N59O49S6
4480.43
10.21
+9
1.57
-0.054
Evidence Records 21 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhi
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

B. avium

Source & Reference

dbAMP DRAMP

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C.
Evidence 3 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-
Evidence 4 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

S. enteriditis

Source & Reference

dbAMP DRAMP

Other

ctive against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. g
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) (
Evidence 6 Activity

Activity

MIC
Antibacterial
2 µg/mL

Target

C. jejuni

Source & Reference

dbAMP DRAMP

Other

ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also
Evidence 7 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

M. gallisepticum

Source & Reference

dbAMP DRAMP

Other

/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also, it kills S. aureus and E. coli. Updated 7/2021, Jan2023 12/
Evidence 8 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhi
Evidence 9 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

B. avium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C.
Evidence 10 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-
Evidence 11 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

S. enteriditis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ctive against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. g
Evidence 12 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

S. typhimurium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) (
Evidence 13 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

C. jejuni

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also
Evidence 14 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

M. gallisepticum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also, it kills S. aureus and E. coli. Updated 7/2021, Jan2023 12/
Evidence 15 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhi
Evidence 16 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

B. avium

Source & Reference

DRAMP

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C.
Evidence 17 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

active against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-
Evidence 18 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

S. enteriditis

Source & Reference

DRAMP

Other

ctive against C. albicans (MIC 8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. g
Evidence 19 Activity

Activity

MIC
Antiparasitic
4 µg/mL

Target

S. typhimurium

Source & Reference

DRAMP

Other

8 ug/ml), B. avium (MIC 16 ug/ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) (
Evidence 20 Activity

Activity

MIC
Antiparasitic
2 µg/mL

Target

C. jejuni

Source & Reference

DRAMP

Other

ml), E. coli (MIC 16 ug/ml), S. enteriditis (MIC 16 ug/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also
Evidence 21 Activity

Activity

MIC
Antiparasitic
16 µg/mL

Target

M. gallisepticum

Source & Reference

DRAMP

Other

/ml), S. typhimurium (MIC 4 ug/ml), C. jejuni (MIC 2 ug/ml), P-multocida (MIC >16 ug/ml), M. gallisepticum (MIC 16 ug/ml) ( Evans et al., 1995 . Also, it kills S. aureus and E. coli. Updated 7/2021, Jan2023 12/