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Peptide record

TPDB11835

Antibacterial Antifungal standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11835
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 39-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KPFKKLEKVGRNIRDGIIKAGPAVAVIGQATSIARPTGK
Physicochemical Analysis
C183H318N56O49
CHMWY
K
4086.88
11.62
9
2
15
+7
10.55
-0.236
95.13
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
5
A
3
R
1
N
1
D
0
C
1
E
1
Q
5
G
0
H
5
I
1
L
6
K
0
M
1
F
3
P
1
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 5 H: 0 I: 5 L: 1 K: 6 M: 0 F: 1 P: 3 S: 1 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
39
C183H318N56O49
4086.88
11.62
+7
10.55
-0.236
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.1 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (M
Evidence 2 Activity

Activity

MIC
Antibacterial
2.6 µM

Target

B. cereus

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraes
Evidence 3 Activity

Activity

MIC
Antibacterial
0.1-0.23 µM

Target

Escherichia coli K12D31 or K12

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 u
Evidence 4 Activity

Activity

MIC
Antibacterial
1.1 µM

Target

P. fluorescent

Source & Reference

dbAMP DRAMP

Other

reus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM),
Evidence 5 Activity

Activity

MIC
Antibacterial
2.1 µM

Target

S. choleraesuis

Source & Reference

dbAMP DRAMP

Other

(MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A.
Evidence 6 Activity

Activity

MIC
Antibacterial
4.0 µM

Target

A. pullulans

Source & Reference

dbAMP DRAMP

Other

r K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxys
Evidence 7 Activity

Activity

MIC
Antibacterial
14.5 µM

Target

A. flavus

Source & Reference

dbAMP DRAMP

Other

fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 8 Activity

Activity

MIC
Antibacterial
16.0 µM

Target

A. fumigatus

Source & Reference

dbAMP DRAMP

Other

, S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 9 Activity

Activity

MIC
Antibacterial
14.6 µM

Target

A. niger

Source & Reference

dbAMP DRAMP

Other

M), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 10 Activity

Activity

MIC
Antibacterial
8.0 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 11 Activity

Activity

MIC
Antifungal
2.1 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (M
Evidence 12 Activity

Activity

MIC
Antifungal
2.6 µM

Target

B. cereus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraes
Evidence 13 Activity

Activity

MIC
Antifungal
0.1-0.23 µM

Target

Escherichia coli K12D31 or K12

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 u
Evidence 14 Activity

Activity

MIC
Antifungal
1.1 µM

Target

P. fluorescent

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

reus (MIC 2.1 uM), B. cereus (MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM),
Evidence 15 Activity

Activity

MIC
Antifungal
2.1 µM

Target

S. choleraesuis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC 2.6 uM), Gram- E. coli K12D31 or K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A.
Evidence 16 Activity

Activity

MIC
Antifungal
4.0 µM

Target

A. pullulans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

r K12 (MIC 0.1-0.23 uM), P. fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxys
Evidence 17 Activity

Activity

MIC
Antifungal
14.5 µM

Target

A. flavus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

fluorescent (MIC 1.1 uM), S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 18 Activity

Activity

MIC
Antifungal
16.0 µM

Target

A. fumigatus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

, S. choleraesuis (MIC 2.1 uM), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 19 Activity

Activity

MIC
Antifungal
14.6 µM

Target

A. niger

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

M), fungi A. pullulans (MIC 4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).
Evidence 20 Activity

Activity

MIC
Antifungal
8.0 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

4.0 uM), A. flavus (MIC 14.5 uM), A. fumigatus (MIC 16.0 uM), A. niger (MIC 14.6 uM), and F. oxysporum (MIC 8.0 uM).