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Peptide record

TPDB11833

Antibacterial Antifungal Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11833
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GSKRWRKFEKRVKKIFEETKEALPVVQGVVAVATAVGRR
Physicochemical Analysis
C201H338N62O52
NDCHMY
V
4455.28
11.50
11
4
16
+7
14.37
-0.482
82.31
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
123.45
4
Residue Composition
number
4
A
5
R
0
N
0
D
0
C
4
E
1
Q
3
G
0
H
1
I
1
L
6
K
0
M
2
F
1
P
1
S
2
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 4 R: 5 N: 0 D: 0 C: 0 E: 4 Q: 1 G: 3 H: 0 I: 1 L: 1 K: 6 M: 0 F: 2 P: 1 S: 1 T: 2 W: 1 Y: 0 V: 7
Chemical Descriptors
39
C201H338N62O52
4455.28
11.50
+7
14.37
-0.482
Evidence Records 6 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
31.3 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 31.3 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 3 Activity

Activity

13% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
13% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 4 Activity

Activity

17% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
17% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 5 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017
Evidence 6 Activity

Activity

20% Killing
Toxicity
500 µg/mL
Cytotoxic
20% Killing | 500 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle. | PLoS One | 2017