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Peptide record

TPDB11832

Antibacterial Antifungal standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11832
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 39-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
QSKKCCGRCSSRMCTKREKEEHTEDCRGSFCCLTHRKKK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C182H312N66O58S8
ANIPWYV
CK
4609.37
9.29
14
5
3
+7
4.22
-1.469
10.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
375
0.08
15
Residue Composition
number
0
A
5
R
0
N
1
D
7
C
4
E
1
Q
2
G
2
H
0
I
1
L
7
K
1
M
1
F
0
P
4
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 7 E: 4 Q: 1 G: 2 H: 2 I: 0 L: 1 K: 7 M: 1 F: 1 P: 0 S: 4 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
39 reviewed residue count
C182H312N66O58S8 sequence-only estimate (linear, free termini)
4609.37 sequence-only estimate (linear, free termini)
9.29 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
4.22 sequence-only estimate (linear, free termini)
-1.469 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Weakly active against E. coli CICC23657 at 100 uM, killing 36.9% and no activity against S.aureus at 100 uM.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Weakly active against E. coli CICC23657 at 100 uM, killing 36.9% and no activity against S.aureus at 100 uM.