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Peptide record

TPDB11831

Antibacterial Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11831
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 39-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ENFFKRIRRAGKRIRDAIISAAPAVETLAQAQKIIKGGD
Physicochemical Analysis
C190H323N61O53
CHMWY
A
4310.03
11.41
9
4
17
+5
11.04
-0.351
95.38
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
5
Residue Composition
number
7
A
5
R
1
N
2
D
0
C
2
E
2
Q
3
G
0
H
6
I
1
L
4
K
0
M
2
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 7 R: 5 N: 1 D: 2 C: 0 E: 2 Q: 2 G: 3 H: 0 I: 6 L: 1 K: 4 M: 0 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
39
C190H323N61O53
4310.03
11.41
+5
11.04
-0.351
Evidence Records 2 records
Evidence 1 Activity

Activity

2.3% Hemolysis
Toxicity
115 µM
Hemolytic Cytotoxic
2.3% Hemolysis | 115 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes. | J Antibiot (Tokyo) | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
1752.3 µM
Hemolytic Cytotoxic
50% Hemolysis | 1752.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and interactions of cationic peptides derived from Galleria mellonella cecropin D-like peptide with model membranes. | J Antibiot (Tokyo) | 2017