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Peptide record

TPDB11829

Antibacterial Antifungal Antiparasitic Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11829
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept dbAMP 3.0
standard
No
A 39-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KWKIFKKIEKAGRNIRDGIIKAGPAVSVVGEAATIYKTG
Physicochemical Analysis
C193H322N54O51
CQHLM
K
4215.01
10.69
9
3
17
+6
8.73
-0.177
95.13
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
165.84
5
Residue Composition
number
5
A
2
R
1
N
1
D
0
C
2
E
0
Q
5
G
0
H
6
I
0
L
7
K
0
M
1
F
1
P
1
S
2
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 5 R: 2 N: 1 D: 1 C: 0 E: 2 Q: 0 G: 5 H: 0 I: 6 L: 0 K: 7 M: 0 F: 1 P: 1 S: 1 T: 2 W: 1 Y: 1 V: 3
Chemical Descriptors
39
C193H322N54O51
4215.01
10.69
+6
8.73
-0.177
Evidence Records 5 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. coli. 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against E. coli. 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli. 7/2021
Evidence 4 Activity

Activity

<10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<10% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
<5% Hemolysis | 100 | µM | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
The Drosophila melanogaster antimicrobial peptides Mtk-1 and Mtk-2 are active against the malarial parasite Plasmodium falciparum. | Parasitol Res | 2019