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Peptide record

TPDB11828

Antibacterial Toxicity standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB11828
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 39-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RSICCSFPDPWGGLCCEDHCSYIGKPGGQCSDKGVCTCN
Physicochemical Analysis
C169H257N49O56S8
AM
C
4127.67
5.32
4
4
7
-1
5.58
-0.256
37.44
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7490
181.46
16
Residue Composition
number
0
A
1
R
1
N
3
D
8
C
1
E
1
Q
6
G
1
H
2
I
1
L
2
K
0
M
1
F
3
P
4
S
1
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 3 C: 8 E: 1 Q: 1 G: 6 H: 1 I: 2 L: 1 K: 2 M: 0 F: 1 P: 3 S: 4 T: 1 W: 1 Y: 1 V: 1
Chemical Descriptors
39
C169H257N49O56S8
4127.67
5.32
-1
5.58
-0.256
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant AfusinC, an anionic fungal CS?? defensin from Aspergillus fumigatus, exhibits antimicrobial activity against gram-positive bacteria | PLoS One | 2018
Evidence 2 Activity

Activity

3.0±0.8% Hemolisis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
3.0±0.8% Hemolisis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Recombinant AfusinC, an anionic fungal CS?? defensin from Aspergillus fumigatus, exhibits antimicrobial activity against gram-positive bacteria | PLoS One | 2018